{"id":"W1770547806","doi":"10.1046/j.1365-2958.2002.02879.x","title":"StoPK‐1, a serine/threonine protein kinase from the glycopeptide antibiotic producer <i>Streptomyces toyocaensis</i> NRRL 15009, affects oxidative stress response","year":2002,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; McMaster University Medical Centre","funders":"Canada Research Chairs","keywords":"Biology; Streptomyces coelicolor; Biochemistry; Autophosphorylation; Kinase; Protein kinase A; Molecular biology; Streptomyces avermitilis; Mutant; Streptomyces; Gene; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004137966,0.0005178979,0.0006842602,0.000117925,0.0001972842,0.00005529337,0.0003937982,0.0003092433,0.0007501178],"category_scores_gemma":[0.0008501358,0.0003280098,0.000234022,0.0004598834,0.000445539,0.00007679642,0.0002538029,0.0005716249,0.000318635],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009934058,"about_ca_system_score_gemma":0.00006876764,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001832829,"about_ca_topic_score_gemma":0.00006458595,"domain_scores_codex":[0.9968788,0.0008016347,0.0004025681,0.00109725,0.0001366496,0.0006831171],"domain_scores_gemma":[0.9980844,0.0002131089,0.0002258193,0.001125928,0.0002035329,0.000147202],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001312861,0.0003263133,0.0003740587,0.0000632043,0.0002750335,0.0005642505,0.0002185161,0.000003099408,0.9850925,0.00002050891,0.0095305,0.002219195],"study_design_scores_gemma":[0.001249274,0.0006691802,0.001177571,0.0003445886,0.0001863511,0.0002529218,0.0000731972,0.000008189112,0.9486142,0.000009266352,0.04702865,0.0003866376],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9719979,0.004329038,0.00001414881,0.02087414,0.00022252,0.00190312,0.0003198913,0.0001282447,0.0002109736],"genre_scores_gemma":[0.9925348,0.00008078595,0.001132722,0.003273094,0.0002693564,0.000009407066,0.0002153478,0.00006644249,0.002418066],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03749814,"threshold_uncertainty_score":0.9999172,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009145983371385507,"score_gpt":0.2155873654906375,"score_spread":0.206441382119252,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}