{"id":"W1773725721","doi":"10.1016/j.febslet.2015.08.009","title":"Loss of histone deacetylase Hdac1 disrupts metabolic processes in intestinal epithelial cells","year":2015,"lang":"en","type":"article","venue":"FEBS Letters","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"HDAC1; Histone deacetylase; Cell biology; Chemistry; Histone; Histone deacetylase 5; HDAC11; Histone deacetylase 2; HDAC10; HDAC4; Biochemistry; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001547148,0.0003786254,0.0003591868,0.0002661445,0.0002002648,0.0004457125,0.0002927986,0.000314713,0.001906888],"category_scores_gemma":[0.00011816,0.0002240649,0.0003608896,0.0002657566,0.000275548,0.0002062794,0.0002057832,0.0007008404,0.0006926463],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004948053,"about_ca_system_score_gemma":0.0003199156,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001756835,"about_ca_topic_score_gemma":0.001888967,"domain_scores_codex":[0.9998143,0.00002423527,0.00002974265,0.0000350557,0.00004337897,0.00005318933],"domain_scores_gemma":[0.9998011,0.00003505089,0.00005252016,0.0000366973,0.0000125735,0.00006203821],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001983261,0.00004062666,0.000170382,0.00002819009,0.000008531302,0.00004097119,0.00000949845,0.00006277251,0.9983208,0.00009608266,0.00006399154,0.000959902],"study_design_scores_gemma":[0.00001742316,0.0001596338,0.003182156,0.000004075642,0.00001538206,0.0001010547,0.00003546213,0.000477102,0.9940177,0.00003477749,0.001952289,0.000002953888],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892648,0.00225241,0.003254362,0.0003385881,0.0001292974,0.00002941266,0.001641085,0.0002536878,0.002836377],"genre_scores_gemma":[0.9921017,0.001340009,0.001563236,0.0001039711,0.00001528187,0.00002823881,0.001051614,0.00005809837,0.003737884],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001906888,"threshold_uncertainty_score":0.006379247,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01737206120964601,"score_gpt":0.3045115873385098,"score_spread":0.2871395261288638,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}