{"id":"W1773882171","doi":"10.1007/s00125-015-3676-7","title":"Suppression of hyperinsulinaemia in growing female mice provides long-term protection against obesity","year":2015,"lang":"en","type":"article","venue":"Diabetologia","topic":"Adipokines, Inflammation, and Metabolic Diseases","field":"Medicine","cited_by":101,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Internal medicine; Endocrinology; Insulin; Hyperinsulinemia; Biology; Insulin tolerance test; Adipose tissue; Brown adipose tissue; Glucose homeostasis; Thermogenesis; Insulin resistance; Medicine; Insulin sensitivity","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003298922,0.0008074236,0.0005261427,0.0004676772,0.0001753972,0.0004928753,0.0006160552,0.0005903938,0.003073195],"category_scores_gemma":[0.0001577075,0.0003688294,0.0005304752,0.0001930787,0.0005384019,0.0004925475,0.0003544463,0.001278064,0.0009106525],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001747372,"about_ca_system_score_gemma":0.0002168852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001406184,"about_ca_topic_score_gemma":0.0003058116,"domain_scores_codex":[0.9998096,0.0000222841,0.00002171895,0.00006539162,0.00003491896,0.00004618707],"domain_scores_gemma":[0.99938,0.00004069482,0.0002935716,0.00007707011,0.00002883483,0.0001798134],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008122078,0.000113221,0.0005391317,0.00004437584,0.00001000937,0.00005969122,0.00001609278,0.00002309773,0.9968002,0.00004617267,0.00003696209,0.001498847],"study_design_scores_gemma":[0.0003799288,0.006791364,0.03985536,0.00005606906,0.0001349431,0.001556991,0.000125822,0.0005374055,0.9460849,0.0001854415,0.004260856,0.00003094358],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930427,0.001944352,0.002658853,0.000237307,0.00008370267,0.00004852412,0.0006381968,0.0003535553,0.00099282],"genre_scores_gemma":[0.9805536,0.002428439,0.004957807,0.000285195,0.000137435,0.0002429517,0.001632173,0.0002479976,0.009514316],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003073195,"threshold_uncertainty_score":0.01028085,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03253459288481479,"score_gpt":0.2766081471284862,"score_spread":0.2440735542436714,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}