{"id":"W1779770448","doi":"10.1023/a:1011348803324","title":"NMR Structure Determination and Structure-Based Functional Characterization of Conserved Hypothetical Protein MTH1175 from Methanobacterium thermoautotrophicum","year":2000,"lang":"en","type":"article","venue":"Journal of Structural and Functional Genomics","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Thermotoga maritima; Methanobacterium; Structural genomics; Biology; Ribonuclease; Hyperthermophile; Protein family; Peptide sequence; Conserved sequence; Nuclear magnetic resonance spectroscopy; Protein structure; Biochemistry; Bacteria; Sequence alignment; Gene; Archaea; Genetics; Stereochemistry; Chemistry; RNA; Escherichia coli","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001474453,0.0002825272,0.0004309338,0.0001420235,0.0001854436,0.0001013954,0.0001090875,0.0002203522,0.003744994],"category_scores_gemma":[0.00003915197,0.0002111792,0.0001021325,0.0001174355,0.0002751272,0.0004389306,0.00002905454,0.000281833,0.000001920155],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000068981,"about_ca_system_score_gemma":0.0001417967,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002079765,"about_ca_topic_score_gemma":0.000009636185,"domain_scores_codex":[0.9982106,0.0001253918,0.0007202798,0.0003073172,0.0004285371,0.0002078367],"domain_scores_gemma":[0.9986798,0.00009434428,0.000607024,0.0001455507,0.000332365,0.000140951],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001526125,0.00001069992,0.0007732678,0.00003384198,0.000038382,0.000003684883,0.00009316778,0.0004216791,0.9889098,0.000204634,0.000007501448,0.007977149],"study_design_scores_gemma":[0.001987639,0.0004322171,0.4825209,0.00005324884,0.0001569555,0.0003538819,0.00003720764,0.002901454,0.5012292,0.009515472,0.0004848044,0.0003270129],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969905,0.000148677,0.001141632,0.0002455287,0.0007189241,0.0001878974,0.0005320576,0.00001550382,0.00001925218],"genre_scores_gemma":[0.9950776,0.00001874095,0.003720917,0.0001771376,0.0007575192,0.000002019506,0.0001568094,0.00002296268,0.00006635958],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4876807,"threshold_uncertainty_score":0.9971657,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01070408822593991,"score_gpt":0.1914339520148308,"score_spread":0.1807298637888909,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}