{"id":"W1779976831","doi":"10.1139/v11-086","title":"Cyclohexylamine oxidase as a useful biocatalyst for the kinetic resolution and dereacemization of amines","year":2011,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Enzyme Catalysis and Immobilization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Centre in Green Chemistry and Catalysis; National Research Council Canada; Biotechnology Research Institute","funders":"","keywords":"Cyclohexylamine; Chemistry; Biocatalysis; Kinetic resolution; Enantiomeric excess; Alkyl; Organic chemistry; Enantiomer; Amine gas treating; Aryl; Formate dehydrogenase; Enzyme; Catalysis; Enantioselective synthesis; Ionic liquid; Cofactor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002368519,0.0003700613,0.0003590083,0.000172272,0.0001073947,0.0004188051,0.0002565621,0.0002415373,0.0004324857],"category_scores_gemma":[0.0001601219,0.0001713118,0.0002103643,0.0002136615,0.0001875045,0.0002026567,0.0002263988,0.0004007043,0.0002120992],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003253608,"about_ca_system_score_gemma":0.0001749888,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001338099,"about_ca_topic_score_gemma":0.001953501,"domain_scores_codex":[0.9997872,0.0000374452,0.00001971205,0.00005078414,0.00006750731,0.00003749859],"domain_scores_gemma":[0.9999013,0.00001886385,0.00002403287,0.00002010522,0.00001310442,0.00002257064],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001433445,0.000005143957,0.00007837306,0.000008695743,0.000001690497,0.00001998098,0.000005054494,0.00001462993,0.999217,0.00001657183,0.000004089738,0.0006143926],"study_design_scores_gemma":[0.000002856536,0.00003322165,0.0007906548,0.000001704593,0.000006124746,0.00008704069,0.000005951453,0.0002188428,0.9982436,0.000007447679,0.0006006251,0.00000205838],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853877,0.002863929,0.009859056,0.0001431371,0.00004006227,0.00003272969,0.0002510015,0.0001126654,0.00130962],"genre_scores_gemma":[0.9852855,0.001265523,0.01090513,0.00002651308,0.000009319579,0.00001484475,0.0004386866,0.00003121905,0.002023445],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001338099,"threshold_uncertainty_score":0.002660692,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01362472219936924,"score_gpt":0.2109592006314875,"score_spread":0.1973344784321183,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}