{"id":"W1782357762","doi":"10.1002/jcb.25401","title":"Statins Modulate Cyclooxygenase‐2 and Microsomal Prostaglandin E Synthase‐1 in Human Hepatic Myofibroblasts","year":2015,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"Liver physiology and pathology","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; Laboratoire d'Excellence Inflamex; American University of Beirut","keywords":"Prenylation; Fluvastatin; Statin; Geranylgeranylation; Pharmacology; Chemistry; Prostaglandin; Simvastatin; Prostaglandin E2; Prostaglandin E; Biochemistry; Enzyme; Biology; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002207747,0.0001872273,0.0002342783,0.0002429151,0.0001214182,0.0001594781,0.00004332263,0.0001673933,0.001119495],"category_scores_gemma":[0.0001756606,0.0001130946,0.0002054946,0.0001302491,0.0001073924,0.0001054382,0.0001117363,0.0002101039,0.0002528888],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001299894,"about_ca_system_score_gemma":0.000160237,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007637408,"about_ca_topic_score_gemma":0.001627609,"domain_scores_codex":[0.9998747,0.00004259045,0.00001334724,0.00001499007,0.00002076493,0.00003366067],"domain_scores_gemma":[0.9999294,0.00001707873,0.00001566692,0.00000883864,0.00001293607,0.00001605605],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006491783,0.00003316269,0.0008092668,0.00004414237,0.000007287108,0.00006516129,0.00002845803,0.00002263556,0.9965709,0.00002700975,0.00002812574,0.001714782],"study_design_scores_gemma":[0.00004871572,0.0007924539,0.02205373,0.000006879252,0.00003994087,0.0002069097,0.00006905469,0.0002786516,0.9748421,0.0000409556,0.001616612,0.000003904216],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929208,0.00511102,0.000829623,0.0001007779,0.00002637092,0.00002917492,0.0002260399,0.00002402632,0.0007321362],"genre_scores_gemma":[0.9950516,0.001755222,0.0006561689,0.0000670516,0.00001762284,0.00003367575,0.0003434827,0.000005005759,0.002070251],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001119495,"threshold_uncertainty_score":0.003745079,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01417056291690029,"score_gpt":0.2602302713043813,"score_spread":0.246059708387481,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}