{"id":"W1783140960","doi":"10.1155/2004/215359","title":"Control the Epithelial Barrier: A Pivotal First Line of Defense","year":2004,"lang":"en","type":"letter","venue":"Canadian Journal of Gastroenterology","topic":"Barrier Structure and Function Studies","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Paracellular transport; Transcellular; Transcytosis; Barrier function; Tight junction; Epithelium; Inflammation; Cell biology; Cytokine; Immunology; Permeability (electromagnetism); Inflammatory bowel disease; Biology; Chemistry; Medicine; Cell; Disease; Pathology; Endocytosis; Membrane; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002390987,0.0003299095,0.0008253541,0.0004280071,0.0003005728,0.0000380125,0.0007269187,0.0003581903,0.0002365922],"category_scores_gemma":[0.0006290976,0.0002229448,0.0004400393,0.000123377,0.001087439,0.00007302868,0.00002893971,0.002087332,0.00001064128],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001451201,"about_ca_system_score_gemma":0.0008956581,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009238292,"about_ca_topic_score_gemma":0.01603284,"domain_scores_codex":[0.9975836,0.0003318427,0.000800595,0.0002744104,0.0002969659,0.000712529],"domain_scores_gemma":[0.997889,0.0002828916,0.0009240212,0.0003356627,0.0002442861,0.000324118],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001252007,0.00001854128,0.009994172,0.00009886957,0.0005051494,0.006638261,0.0008274121,0.000436362,0.001028666,0.0001856911,0.9787378,0.0002770764],"study_design_scores_gemma":[0.003330779,0.003323265,0.001609464,0.0001091405,0.0003624083,0.008309111,0.00003479003,0.000005758593,0.0004117293,0.0009420358,0.9813734,0.0001881022],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.06726318,0.0004447578,0.001685342,0.920225,0.007987924,0.0003731476,0.001562479,0.00001114346,0.0004470763],"genre_scores_gemma":[0.6130128,0.00002983461,0.00001517015,0.3841927,0.002608377,0.000003873481,0.000002296897,0.0000261224,0.0001087678],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.5457496,"threshold_uncertainty_score":0.9091423,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01478348352696064,"score_gpt":0.206182026030016,"score_spread":0.1913985425030554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}