{"id":"W1785726601","doi":"10.1152/ajplung.2001.281.5.l1240","title":"Direct and indirect bacterial killing functions of neutrophil defensins in lung explants","year":2001,"lang":"en","type":"article","venue":"American Journal of Physiology-Lung Cellular and Molecular Physiology","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Mount Sinai Hospital; Toronto General Hospital; St. Michael's Hospital","funders":"","keywords":"Microbiology; Pseudomonas aeruginosa; Antimicrobial; Bacteria; Lung; Defensin; Biology; Explant culture; Antimicrobial peptides; Chemistry; In vitro; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003792844,0.0007416151,0.0004650375,0.0001765551,0.0001233347,0.0004519659,0.0002294982,0.000376391,0.001495798],"category_scores_gemma":[0.0002476956,0.0001628741,0.0002532986,0.0001054527,0.0003293335,0.0004873979,0.0003392479,0.0007258001,0.0005961905],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002374747,"about_ca_system_score_gemma":0.0002045032,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002099568,"about_ca_topic_score_gemma":0.0004413966,"domain_scores_codex":[0.9996709,0.00009802259,0.00003075327,0.00007455707,0.00006763271,0.00005808926],"domain_scores_gemma":[0.9997517,0.00008055078,0.00004666859,0.00003171477,0.00003098846,0.00005823841],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009629304,0.00001297866,0.0001253088,0.00007858459,0.000002481618,0.00005093205,0.00001542031,0.00001588615,0.9987545,0.00002224229,0.000007674146,0.0008177535],"study_design_scores_gemma":[0.00001306541,0.0007383138,0.005824913,0.00002286094,0.00001370968,0.0002489048,0.00006093611,0.0002808651,0.9916816,0.00002494757,0.001086546,0.000003349086],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9808041,0.01117126,0.004437367,0.0001076955,0.000061435,0.00005782065,0.0003803311,0.0000672233,0.002912732],"genre_scores_gemma":[0.9865998,0.003869112,0.004864919,0.0001153373,0.00003912591,0.0001052213,0.0005358062,0.00002075438,0.003849857],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001495798,"threshold_uncertainty_score":0.005003989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005314693044030188,"score_gpt":0.2026664545329571,"score_spread":0.1973517614889269,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}