{"id":"W1791415390","doi":"10.1002/jms.3448","title":"Direct targeted glycation of the free sulfhydryl group of cysteine residue (Cys‐34) of BSA. Mapping of the glycation sites of the anti‐tumor Thomsen–Friedenreich neoglycoconjugate vaccine prepared by Michael addition reaction","year":2014,"lang":"en","type":"article","venue":"Journal of Mass Spectrometry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Fisheries and Oceans Canada; Université du Québec à Montréal; Health Sciences Centre; Memorial University of Newfoundland","funders":"","keywords":"Chemistry; Glycation; Glycoconjugate; Mass spectrometry; Electrospray ionization; Chromatography; Dehydroalanine; Glycan; Matrix-assisted laser desorption/ionization; Peptide; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001257267,0.0001751791,0.0004526104,0.0002308417,0.00007378028,0.000009430227,0.0006905088,0.0001615983,0.00003653179],"category_scores_gemma":[0.001533899,0.0001073633,0.0003383386,0.0008444641,0.0001515549,0.00003213552,0.0001670471,0.0002565887,2.903795e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005972652,"about_ca_system_score_gemma":0.0001331031,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001466023,"about_ca_topic_score_gemma":0.00007871502,"domain_scores_codex":[0.9972203,0.0005014752,0.001099356,0.0002065366,0.000781543,0.0001907237],"domain_scores_gemma":[0.9953938,0.0001109044,0.002732406,0.0008314515,0.0008853187,0.00004613534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005298546,0.0001737899,0.01062224,0.0002014706,0.0001467103,2.077211e-7,0.00007077166,0.00008532254,0.9868025,0.0001242741,0.001098877,0.0001439621],"study_design_scores_gemma":[0.001236144,0.000595384,0.09996695,0.0002118803,0.00006769298,0.00002167409,0.0001544418,0.0001923217,0.8966355,0.0003022273,0.0005302829,0.00008544458],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99632,0.0006249932,0.001062884,0.0005690505,0.0001760082,0.0004708144,0.0001291444,0.000003252499,0.0006438599],"genre_scores_gemma":[0.9987132,0.0001439056,0.0006971322,0.00002037585,0.000141662,0.000005970087,0.00005158035,0.00001955773,0.0002065963],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09016696,"threshold_uncertainty_score":0.4378148,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006007950796344665,"score_gpt":0.2239891327265819,"score_spread":0.2179811819302372,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}