{"id":"W1793552777","doi":"10.14740/gr689w","title":"Curcumin Relaxes Precontracted Guinea Pig Gallbladder Strips via Multiple Signaling Pathways","year":2015,"lang":"en","type":"article","venue":"Gastroenterology Research","topic":"Curcumin's Biomedical Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Curcumin; Protein kinase C; Pharmacology; Protein kinase A; Guinea pig; Tetraethylammonium chloride; Chemistry; Kinase; Medicine; Biophysics; Biochemistry; Biology; Endocrinology; Potassium","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003124242,0.0005098685,0.0004011845,0.0001827414,0.000195997,0.0002261899,0.0002039706,0.0003003359,0.002973336],"category_scores_gemma":[0.0002274891,0.0002561549,0.0004959213,0.0001243524,0.000281034,0.0003207603,0.0002772443,0.0009053322,0.0004181064],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002948292,"about_ca_system_score_gemma":0.0003830419,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006521285,"about_ca_topic_score_gemma":0.001478744,"domain_scores_codex":[0.999853,0.00003613782,0.00001484998,0.00002707104,0.00002560166,0.0000432662],"domain_scores_gemma":[0.9998295,0.00005992449,0.00003441066,0.00002121366,0.00002291553,0.00003194735],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007860256,0.00005523189,0.0001235303,0.0001337747,0.00001139511,0.0001209348,0.00002719606,0.00002439283,0.9975885,0.00002242119,0.00005709883,0.001049386],"study_design_scores_gemma":[0.0002234859,0.004693449,0.01941397,0.00005169994,0.0001124995,0.0004357097,0.0001307394,0.0006443593,0.970498,0.00005913695,0.003722784,0.00001417987],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909115,0.005336858,0.001039898,0.0004282338,0.0001184465,0.00005096738,0.0002470073,0.00003070157,0.001836377],"genre_scores_gemma":[0.9846257,0.005613837,0.003269268,0.0003576035,0.0001386697,0.0001062745,0.0007524423,0.00003321738,0.005103121],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002973336,"threshold_uncertainty_score":0.009946823,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09795481571363804,"score_gpt":0.3368087360265093,"score_spread":0.2388539203128713,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}