{"id":"W1798755157","doi":"10.1016/j.coviro.2015.09.005","title":"Interplay between the virus and the ubiquitin–proteasome system: molecular mechanism of viral pathogenesis","year":2015,"lang":"en","type":"review","venue":"Current Opinion in Virology","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":170,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; St. Paul's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Biology; Viral pathogenesis; Ubiquitin; Proteasome; Mechanism (biology); Cell biology; Function (biology); Pathogenesis; Viral entry; Immune system; Viral protein; Virus; Virology; Viral replication; Immunology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008279242,0.0009073539,0.001509534,0.001147539,0.000248555,0.001693027,0.00127736,0.001977953,0.00190726],"category_scores_gemma":[0.0005031092,0.0002316537,0.000372461,0.001483529,0.0008754093,0.002053968,0.0009290941,0.001825034,0.001351974],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001061053,"about_ca_system_score_gemma":0.001210039,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005984038,"about_ca_topic_score_gemma":0.001031623,"domain_scores_codex":[0.9997812,0.00003758243,0.00002153568,0.00004035221,0.00008424695,0.00003499678],"domain_scores_gemma":[0.999724,0.0001002437,0.00005279893,0.00001064311,0.00006875006,0.00004357293],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000147692,0.00004937881,0.0003506162,0.01094862,0.00010458,0.000386244,0.00005527297,0.0007223017,0.008979893,0.01056776,0.03148182,0.9362058],"study_design_scores_gemma":[0.0000229978,0.0000837777,0.001064832,0.001998001,0.0001210652,0.001574947,0.0001068927,0.0003507553,0.001890253,0.007927774,0.9848203,0.00003832274],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001445944,0.9984419,0.0002300492,0.0004659869,0.0002143656,0.000002078287,0.000009104055,0.000006469059,0.0004855688],"genre_scores_gemma":[0.001213623,0.9977906,0.0001770145,0.0002090299,0.0002770416,0.00000268919,0.00001972768,8.534854e-7,0.0003093619],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001977953,"threshold_uncertainty_score":0.007698536,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05217656352987564,"score_gpt":0.3555601631498262,"score_spread":0.3033835996199506,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}