{"id":"W1798755157","doi":"10.1016/j.coviro.2015.09.005","title":"Interplay between the virus and the ubiquitin–proteasome system: molecular mechanism of viral pathogenesis","year":2015,"lang":"en","type":"review","venue":"Current Opinion in Virology","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":170,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; St. Paul's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Biology; Viral pathogenesis; Ubiquitin; Proteasome; Mechanism (biology); Cell biology; Function (biology); Pathogenesis; Viral entry; Immune system; Viral protein; Virus; Virology; Viral replication; Immunology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001874532,0.0005072611,0.001478683,0.000139341,0.00008336313,0.00002565289,0.0008259168,0.0006167018,0.000006733499],"category_scores_gemma":[0.0001512485,0.000295753,0.0004091949,0.0001648221,0.0005218851,0.000004054341,0.0007529149,0.0005398233,0.00001464792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004179823,"about_ca_system_score_gemma":0.0002324688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002164576,"about_ca_topic_score_gemma":0.000002096828,"domain_scores_codex":[0.9957815,0.001994098,0.0009450756,0.0006404981,0.0002343092,0.0004045012],"domain_scores_gemma":[0.9982088,0.0001357477,0.0006676678,0.0008033196,0.00008560171,0.00009890428],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002827172,0.000123847,0.00004430097,0.02527158,0.0005339067,0.000005204437,0.0002874401,0.000002698619,0.00143169,0.03941614,0.0005766155,0.9320239],"study_design_scores_gemma":[0.001229794,0.0003510883,0.000009725436,0.003024985,0.000348074,0.0000987649,0.00004818957,0.00001738095,0.0008483688,0.0009690694,0.9926292,0.000425417],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001082083,0.9938523,0.0009675802,0.00005142842,0.001602884,0.001936011,0.0003777759,0.00001402272,0.0001159021],"genre_scores_gemma":[0.006223138,0.9915072,0.00004097068,0.00002647614,0.0007766429,0.00088379,0.000467652,0.00006325223,0.00001083523],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9920526,"threshold_uncertainty_score":0.9999495,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05217656352987564,"score_gpt":0.3555601631498262,"score_spread":0.3033835996199506,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}