{"id":"W1806788033","doi":"10.1039/c5ob01115a","title":"Disulfide-bridged peptide macrobicycles from nature","year":2015,"lang":"en","type":"review","venue":"Organic & Biomolecular Chemistry","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Toronto Public Health","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Disulfide bond; Peptide; Combinatorial chemistry; Stereochemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002372683,0.0007254975,0.0005715602,0.001646255,0.0002666675,0.0006618813,0.0004744509,0.0005214963,0.002703964],"category_scores_gemma":[0.0002408591,0.0002737076,0.0001938219,0.001382135,0.0002883963,0.0008997263,0.0006623921,0.001248402,0.001976713],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005134595,"about_ca_system_score_gemma":0.0005407265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004407503,"about_ca_topic_score_gemma":0.0009185152,"domain_scores_codex":[0.999899,0.000009165699,0.00001213971,0.00001994931,0.00004663151,0.00001309287],"domain_scores_gemma":[0.99994,0.00001751865,0.00001260147,0.000002659022,0.00001530699,0.00001190296],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005744006,0.00006155424,0.00009575522,0.01224382,0.00004072493,0.0002455751,0.00006263643,0.0004516339,0.02262047,0.01052935,0.01611108,0.93748],"study_design_scores_gemma":[0.000007648949,0.00006455127,0.0002720357,0.0006412896,0.00001950839,0.0006136879,0.00001816039,0.00005599905,0.005044615,0.001174821,0.9920738,0.00001381219],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00087365,0.9936073,0.00082715,0.0002009762,0.0003435809,0.00001718702,0.00005344463,0.00003247584,0.004044259],"genre_scores_gemma":[0.004827671,0.9900384,0.0008838866,0.0002400541,0.0001245814,0.00002751041,0.0001391603,0.000005689256,0.003713049],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002703964,"threshold_uncertainty_score":0.00904566,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01072797319784373,"score_gpt":0.2805048930496833,"score_spread":0.2697769198518396,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}