{"id":"W1807669271","doi":"10.1002/9780470921920.edm087","title":"Idiosyncratic Drug Reactions","year":2012,"lang":"en","type":"other","venue":"Encyclopedia of Drug Metabolism and Interactions","topic":"Drug-Induced Adverse Reactions","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Mechanism (biology); Drug; Circumstantial evidence; Drug reaction; Immune system; Population; Biology; Computational biology; Immunology; Pharmacology; Medicine; Environmental health","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001078889,0.0008600652,0.0008635371,0.001002508,0.0006143329,0.001121773,0.0004730208,0.001008839,0.02493796],"category_scores_gemma":[0.004276021,0.0001559818,0.0009783803,0.001317188,0.000437511,0.0005262024,0.0008836287,0.00151097,0.01056569],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005615365,"about_ca_system_score_gemma":0.0006746855,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008888287,"about_ca_topic_score_gemma":0.0009780579,"domain_scores_codex":[0.9973611,0.0006044799,0.0004626891,0.0002505936,0.001016834,0.0003042413],"domain_scores_gemma":[0.9956356,0.0008718761,0.001527664,0.0005240012,0.001166655,0.0002742553],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001488278,0.0005469291,0.06023264,0.009987313,0.000707771,0.03314134,0.0005845285,0.0006306851,0.02228683,0.007948969,0.1783688,0.684076],"study_design_scores_gemma":[0.0002102274,0.0009922434,0.04363603,0.003109211,0.0004542657,0.102281,0.0003310159,0.0005054617,0.01654781,0.003796589,0.8280593,0.00007687514],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.1133933,0.298844,0.04025746,0.01265767,0.005021073,0.0040974,0.01583153,0.00335903,0.5065386],"genre_scores_gemma":[0.7113883,0.07819774,0.008929745,0.02169138,0.002433359,0.0008611488,0.008231681,0.0002909493,0.1679757],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.02493796,"threshold_uncertainty_score":0.08342576,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01033229284861725,"score_gpt":0.2710312877869642,"score_spread":0.2606989949383469,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}