{"id":"W1816027866","doi":"10.1002/bmc.2834","title":"Stereospecific analytical method development and preliminary <i>in vivo</i> pharmacokinetic characterization of pinostrobin in the rat","year":2012,"lang":"en","type":"article","venue":"Biomedical Chromatography","topic":"Ginseng Biological Effects and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"University of Manitoba","keywords":"Chemistry; Enantiomer; Chromatography; Pharmacokinetics; Calibration curve; Resolution (logic); Detection limit; In vivo; Stereochemistry; Pharmacology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004376116,0.0001077846,0.0001388927,0.00009493366,0.00002763697,0.000007596044,0.0001307295,0.0001094733,0.00001711139],"category_scores_gemma":[0.00001780227,0.0000700353,0.00004189396,0.0003524513,0.000159189,0.000003948085,0.00005614902,0.00007888254,0.000001077305],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004084487,"about_ca_system_score_gemma":0.0000155343,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003261519,"about_ca_topic_score_gemma":9.130053e-7,"domain_scores_codex":[0.9990869,0.0001399214,0.000256531,0.0001866381,0.0001176133,0.0002124198],"domain_scores_gemma":[0.9996734,0.00004616809,0.00005390274,0.0001344412,0.00001167795,0.00008046036],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0000427925,0.000408208,0.02141208,0.00003893835,0.00001359583,0.000001472648,0.0001291856,2.220353e-7,0.9717399,0.0002719677,0.0002161046,0.005725495],"study_design_scores_gemma":[0.001022569,0.0003827671,0.6360099,0.00004655754,0.00002249395,0.00003041027,0.0001092275,0.0001764456,0.2355336,0.00001753169,0.1264205,0.0002280686],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967076,0.000309494,0.002344229,0.0002095377,0.00004214084,0.0002618693,0.00001121031,0.000004917537,0.0001090442],"genre_scores_gemma":[0.9978919,0.00009350447,0.001529939,0.000220101,0.00007103744,0.00006626332,0.0001141366,0.000005815383,0.000007284985],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7362064,"threshold_uncertainty_score":0.2855957,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01370729746549881,"score_gpt":0.2789972097495305,"score_spread":0.2652899122840317,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}