{"id":"W1818129319","doi":"10.1586/14737159.2015.1063421","title":"Predictive and prognostic cancer biomarkers revisited","year":2015,"lang":"en","type":"review","venue":"Expert Review of Molecular Diagnostics","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Cancer; Medicine; Oncology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006784641,0.001451286,0.002782405,0.004886194,0.0006074688,0.00344204,0.002346124,0.004281639,0.00307779],"category_scores_gemma":[0.007599196,0.0006453069,0.001366255,0.003894434,0.004700886,0.006548946,0.002076203,0.01012376,0.002495687],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004274586,"about_ca_system_score_gemma":0.003840354,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002636858,"about_ca_topic_score_gemma":0.002697972,"domain_scores_codex":[0.9974355,0.000960476,0.0002889394,0.0004073172,0.0007724467,0.0001353735],"domain_scores_gemma":[0.9941319,0.003827558,0.0003639831,0.0001674088,0.001297052,0.0002120905],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001272349,0.00006036204,0.0006749254,0.009992302,0.0001922275,0.0003643899,0.0002687706,0.0006461512,0.0008400951,0.1033899,0.07810836,0.8053352],"study_design_scores_gemma":[0.00002471101,0.0001045112,0.0009560154,0.007759826,0.0001206617,0.002469922,0.0001965115,0.000421479,0.0004318739,0.05093536,0.9365171,0.00006206171],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008733498,0.9882243,0.001084547,0.008304177,0.001033888,0.000007960966,0.00002566701,0.00001774104,0.0012144],"genre_scores_gemma":[0.003839865,0.9823185,0.001547846,0.007905519,0.002669125,0.00003746956,0.00006720707,0.00001071879,0.001603734],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006784641,"threshold_uncertainty_score":0.0358811,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01873979675133194,"score_gpt":0.3432180555444364,"score_spread":0.3244782587931044,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}