{"id":"W1818745376","doi":"10.1111/j.1365-2958.2005.04688.x","title":"Mapping of essential replication functions of the linear plasmid lp17 of <i>B. burgdorferi</i> by targeted deletion walking","year":2005,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Vector-borne infectious diseases","field":"Immunology and Microbiology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Western University","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Biology; Plasmid; Replicon; Genetics; Origin of replication; Gene; Autonomously replicating sequence; Genome; DNA replication; Borrelia burgdorferi","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001873874,0.0001656917,0.0003450617,0.0001257638,0.00008937418,0.000001799461,0.0002683613,0.0002977379,0.0002081052],"category_scores_gemma":[0.0001674249,0.0001434442,0.0002259652,0.0002823973,0.0004489322,0.00003658015,0.000121204,0.0001882769,0.00002913246],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004088286,"about_ca_system_score_gemma":0.00007008958,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009743572,"about_ca_topic_score_gemma":0.00001352132,"domain_scores_codex":[0.9984795,0.00033668,0.000579058,0.0003393765,0.00002479589,0.0002405637],"domain_scores_gemma":[0.9985539,0.0000755095,0.0005309051,0.0006157902,0.0002106203,0.00001331179],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007076185,0.0002270831,0.001622454,0.00003299141,0.0002512287,2.606593e-7,0.0001112833,0.0002503033,0.9940053,0.0001398198,0.002586592,0.0007019031],"study_design_scores_gemma":[0.0006599114,0.0001064362,0.001349214,0.00003234762,0.00008054195,0.00005437759,0.00004582839,0.0000119759,0.9722203,0.00001729633,0.02530609,0.0001156677],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911787,0.002663489,0.00477579,0.0002388872,0.0003524153,0.0002975532,0.0002930108,0.0000376408,0.0001625242],"genre_scores_gemma":[0.9989299,0.00003155686,0.0001443159,0.0001476498,0.00002024217,0.00001891997,0.0005430555,0.00001919295,0.000145126],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0227195,"threshold_uncertainty_score":0.5849485,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004333814178876065,"score_gpt":0.2078185009443163,"score_spread":0.2034846867654402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}