{"id":"W1819484237","doi":"10.1200/jco.2009.27.15_suppl.lba4505","title":"ESPAC-3(v2): A multicenter, international, open-label, randomized controlled phase III trial of adjuvant 5-fluorouracil/folinic acid (5-FU/FA) versus gemcitabine (GEM) in patients with resected pancreatic ductal adenocarcinoma","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Folinic acid; Gemcitabine; Fluorouracil; Oncology; Internal medicine; Pancreatic ductal adenocarcinoma; Adjuvant; Clinical trial; Adenocarcinoma; Adjuvant chemotherapy; Chemotherapy; Pancreatic cancer; Cancer; Breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002094806,0.002496473,0.002115269,0.0006078983,0.000463649,0.001420746,0.001385151,0.001943499,0.007635479],"category_scores_gemma":[0.001505222,0.0006855949,0.001996636,0.0006818846,0.001343159,0.001868773,0.0005867307,0.004613115,0.001538838],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001005008,"about_ca_system_score_gemma":0.001634017,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001410618,"about_ca_topic_score_gemma":0.004142475,"domain_scores_codex":[0.9995202,0.000265123,0.0000255434,0.00007154483,0.00003417908,0.00008348849],"domain_scores_gemma":[0.9993922,0.0001106662,0.0001291356,0.00005078766,0.00003847,0.0002787903],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.954048,0.00862502,0.0008465536,0.0009543846,0.001218977,0.00006767005,0.0001015245,0.0008372286,0.004301578,0.0003281681,0.003382538,0.02528832],"study_design_scores_gemma":[0.957527,0.03948941,0.0009655482,0.00002745344,0.0002791561,0.00005039483,0.00003214264,0.0003729389,0.0003130834,0.0001629315,0.0007661209,0.00001377132],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9767107,0.007419871,0.001041699,0.001864794,0.0008634896,0.004223548,0.0027404,0.0004250028,0.004710491],"genre_scores_gemma":[0.9656959,0.005867478,0.00394766,0.004914022,0.0009154684,0.006073933,0.005641169,0.0001058437,0.006838547],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007635479,"threshold_uncertainty_score":0.02554321,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1223693787165505,"score_gpt":0.4938760090073279,"score_spread":0.3715066302907774,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}