{"id":"W1819549772","doi":"10.1186/1477-5956-3-3","title":"Target selection of soluble protein complexes for structural proteomics studies.","year":2005,"lang":"en","type":"article","venue":"Proteome Science","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Structural genomics; Proteomics; Computational biology; Denaturation (fissile materials); Protein domain; Solubility; Biology; Biochemistry; Recombinant DNA; Gene; Chemistry; Protein structure","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009000431,0.000914676,0.0007755495,0.0007026902,0.0003123224,0.0006111751,0.0005130926,0.0005498593,0.00265797],"category_scores_gemma":[0.000705128,0.0003593825,0.0005224292,0.0008184263,0.0002300981,0.0004149727,0.0003742306,0.0007154536,0.002596334],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005163178,"about_ca_system_score_gemma":0.0002638939,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002360055,"about_ca_topic_score_gemma":0.0006084304,"domain_scores_codex":[0.9993606,0.0001197084,0.00006974678,0.0001567131,0.0002316882,0.00006161845],"domain_scores_gemma":[0.9995197,0.00013101,0.00009566167,0.00006135761,0.0001460491,0.00004622275],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000574021,0.00003287087,0.0002104617,0.0001311282,0.00001191484,0.0000379619,0.00001123739,0.00006692566,0.9971078,0.00007120273,0.0002146094,0.002046487],"study_design_scores_gemma":[0.00001515714,0.0001408849,0.001638195,0.0000134086,0.00003188144,0.0003098331,0.00001753209,0.001886373,0.9880893,0.00009949179,0.007750646,0.000007171064],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.6900615,0.01062664,0.2793065,0.0007456936,0.00027675,0.001337019,0.009943111,0.001805872,0.005896939],"genre_scores_gemma":[0.6510682,0.006271392,0.2946646,0.0005978842,0.0001159081,0.001259331,0.03385147,0.001179288,0.01099208],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.00265797,"threshold_uncertainty_score":0.008891821,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01959439373701482,"score_gpt":0.2986260202663318,"score_spread":0.279031626529317,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}