{"id":"W1822356101","doi":"10.1212/wnl.82.10_supplement.p3.169","title":"Subgroup and Sensitivity Analyses of the Primary Endpoint from the Peginterferon Beta-1a ADVANCE Study: A Pivotal Phase 3 Study in Patients with Relapsing-Remitting Multiple Sclerosis (P3.169)","year":2014,"lang":"en","type":"article","venue":"Neurology","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"","keywords":"Multiple sclerosis; Relapsing remitting; Medicine; Clinical endpoint; BETA (programming language); Internal medicine; Oncology; Pediatrics; Immunology; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.07029257,0.002437526,0.00396438,0.001451401,0.000469456,0.001516934,0.001310644,0.001764036,0.003332226],"category_scores_gemma":[0.07400042,0.0008380848,0.0281521,0.001205011,0.0006189458,0.001030061,0.001511098,0.002552934,0.0002958781],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001236267,"about_ca_system_score_gemma":0.001250913,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001532122,"about_ca_topic_score_gemma":0.002416446,"domain_scores_codex":[0.9267401,0.06108815,0.004779556,0.003164254,0.003258404,0.0009697157],"domain_scores_gemma":[0.9340066,0.05163671,0.004912433,0.007274713,0.001795608,0.0003738428],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.4854492,0.001041399,0.05524227,0.009582788,0.356808,0.00120587,0.0004615178,0.0291538,0.00959344,0.002274398,0.006297066,0.04289014],"study_design_scores_gemma":[0.09790485,0.05028028,0.2191908,0.001357797,0.5200911,0.002369303,0.0005602447,0.04933414,0.01734191,0.01631106,0.02442912,0.0008294216],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8580716,0.05605892,0.04287101,0.001080514,0.00132906,0.01302134,0.01952566,0.0006341717,0.007407649],"genre_scores_gemma":[0.978581,0.001646283,0.00821496,0.0006969868,0.0001820888,0.005268692,0.004377227,0.0001003475,0.000932309],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07029257,"threshold_uncertainty_score":0.3717471,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0552380320770437,"score_gpt":0.3117089507500696,"score_spread":0.2564709186730259,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}