{"id":"W1826495180","doi":"10.4137/ijtr.s26862","title":"Tryptophan Catabolism in Chronic Viral Infections: Handling Uninvited Guests","year":2015,"lang":"en","type":"review","venue":"International Journal of Tryptophan Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":128,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Immune system; Kynurenine; Indoleamine 2,3-dioxygenase; Biology; Aryl hydrocarbon receptor; Virus; Hepatitis C virus; Immunology; Immunosuppression; Virology; Tryptophan; Amino acid; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.002971122,0.0005675096,0.001613686,0.004922142,0.0001700421,0.0004945707,0.003260246,0.0005291326,0.0002226426],"category_scores_gemma":[0.004314397,0.0004821897,0.0007122165,0.00205002,0.0004874746,0.0007737214,0.000605189,0.003397346,0.0003046701],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002866605,"about_ca_system_score_gemma":0.004300994,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008420883,"about_ca_topic_score_gemma":0.00006718673,"domain_scores_codex":[0.9910181,0.001970597,0.001919937,0.0007324459,0.003418566,0.0009404215],"domain_scores_gemma":[0.9951894,0.001526093,0.001016942,0.0005004018,0.001329911,0.000437285],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001399677,0.0006361335,0.00001245249,0.001151412,0.0001649469,0.001737624,0.0003211918,0.00008778006,0.0008254051,0.002210253,0.003750787,0.9889621],"study_design_scores_gemma":[0.002124194,0.000391837,0.00001659631,0.008044389,0.00003301665,0.001058323,0.00006645127,0.0000669625,0.0009129668,0.002471803,0.9843738,0.0004396561],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002117548,0.9921262,0.00005635123,0.0002731809,0.003135864,0.0007238012,0.00009043898,0.00004174501,0.001434933],"genre_scores_gemma":[0.003819243,0.9923739,0.00009201597,0.00008413714,0.002786661,0.00006299057,0.00003698841,0.0001107076,0.000633304],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9885224,"threshold_uncertainty_score":0.999763,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2111456606716264,"score_gpt":0.4876596429381626,"score_spread":0.2765139822665362,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}