{"id":"W1826495180","doi":"10.4137/ijtr.s26862","title":"Tryptophan Catabolism in Chronic Viral Infections: Handling Uninvited Guests","year":2015,"lang":"en","type":"review","venue":"International Journal of Tryptophan Research","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":128,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Immune system; Kynurenine; Indoleamine 2,3-dioxygenase; Biology; Aryl hydrocarbon receptor; Virus; Hepatitis C virus; Immunology; Immunosuppression; Virology; Tryptophan; Amino acid; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002377921,0.0004229506,0.0007093732,0.001053853,0.0002412976,0.0007338987,0.0004440683,0.0007723891,0.002710902],"category_scores_gemma":[0.0003544965,0.0001272314,0.0003843872,0.0006319046,0.0002912612,0.0007837827,0.0005020619,0.0008404612,0.00114213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000341406,"about_ca_system_score_gemma":0.0005976622,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008412969,"about_ca_topic_score_gemma":0.001706631,"domain_scores_codex":[0.999921,0.00001725616,0.00001558839,0.00001422063,0.00002105928,0.00001087749],"domain_scores_gemma":[0.9999132,0.00003625291,0.00001513441,0.000003408019,0.00002125738,0.00001071476],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001378919,0.00008489009,0.0003877091,0.01682485,0.00009604008,0.0004029984,0.0001155697,0.0001874697,0.003768184,0.002814133,0.01502277,0.9601574],"study_design_scores_gemma":[0.00002950322,0.0002521609,0.002670745,0.004479768,0.000171179,0.005473448,0.0001673835,0.0001481893,0.001935836,0.00334821,0.9812983,0.00002517199],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004824376,0.9977491,0.0001682245,0.0002134261,0.0001283671,0.000005711061,0.00001929271,0.000007795345,0.001225628],"genre_scores_gemma":[0.002883499,0.9956499,0.0002945279,0.0001246468,0.0001332672,0.00001032798,0.00003837887,0.000002049988,0.0008634978],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002710902,"threshold_uncertainty_score":0.009068906,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2111456606716264,"score_gpt":0.4876596429381626,"score_spread":0.2765139822665362,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}