{"id":"W1826601058","doi":"10.3233/jpd-130198","title":"Continuous Real-Time in vivo Measurement of Cerebral Nitric Oxide Supports Theoretical Predictions of an Irreversible Switching in Cerebral ROS after Sufficient Exposure to External Toxins","year":2013,"lang":"en","type":"article","venue":"Journal of Parkinson s Disease","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Group for Research in Decision Analysis","funders":"Science Foundation Ireland; Higher Education Authority","keywords":"Neurochemical; Nitric oxide; Neuroscience; Bistability; Endogeny; Reactive oxygen species; Chemistry; Biophysics; Medicine; Internal medicine; Biology; Biochemistry; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004505395,0.000286061,0.0002358899,0.0001500082,0.0001013727,0.0002703915,0.0003547878,0.0003262314,0.0004072556],"category_scores_gemma":[0.001322456,0.0001123156,0.0002840184,0.00009272436,0.0005572448,0.0004088509,0.0002202558,0.0004608793,0.0000852915],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004572141,"about_ca_system_score_gemma":0.0002285677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008957215,"about_ca_topic_score_gemma":0.0007170345,"domain_scores_codex":[0.9998549,0.00002022658,0.00001113174,0.00005073511,0.00004642038,0.00001665592],"domain_scores_gemma":[0.9990952,0.0004073927,0.0002605265,0.0001249618,0.00007043174,0.0000416501],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003818359,0.0001164859,0.008644924,0.0001236852,0.00004567333,0.0001955254,0.00009650342,0.03467654,0.9474906,0.002180122,0.0000983396,0.00594972],"study_design_scores_gemma":[0.00003029509,0.0007004701,0.04681468,0.00002051026,0.00005997632,0.0003095792,0.00007270464,0.5346599,0.4109157,0.005782316,0.0005898505,0.00004411038],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8983077,0.0003309642,0.1001366,0.0001915271,0.00002490046,0.0000166389,0.0001131893,0.0001496175,0.0007288563],"genre_scores_gemma":[0.9954868,0.0001230336,0.004198999,0.00001916604,0.000003609592,0.0000135872,0.00005638264,0.000006529478,0.00009182614],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008957215,"threshold_uncertainty_score":0.003317297,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008894073492775321,"score_gpt":0.2412322784299652,"score_spread":0.2323382049371899,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}