{"id":"W1826960795","doi":"10.1016/j.neuroscience.2015.10.031","title":"Adenosine receptor targets for pain","year":2015,"lang":"en","type":"review","venue":"Neuroscience","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":194,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Adenosine; Medicine; Neuropathic pain; Pharmacology; Adenosine receptor; Nociception; Adenosine kinase; Chronic pain; Caffeine; Adenosine A2A receptor; Nociceptor; Adenosine A1 receptor; Agonist; Receptor; Neuroscience; Internal medicine; Biology; Adenosine deaminase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006813457,0.0002823726,0.0004968291,0.00005618292,0.00009567304,0.00004107114,0.0005456451,0.0002270639,0.000009357599],"category_scores_gemma":[0.000743067,0.000230042,0.0002405286,0.0001974324,0.00009232794,0.000003316828,0.0001424885,0.0001213156,0.00001439173],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001560597,"about_ca_system_score_gemma":0.0003521238,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001386715,"about_ca_topic_score_gemma":1.834495e-7,"domain_scores_codex":[0.9984016,0.0001460926,0.0002864793,0.0006559879,0.0001786032,0.0003312729],"domain_scores_gemma":[0.9991612,0.00004089026,0.000183381,0.0003803803,0.0000937019,0.0001404097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001060326,0.0000498704,0.000002798673,0.001856462,0.000008969225,0.000004398275,0.000006342362,0.00000837505,0.001399442,0.00003799294,0.5444358,0.452179],"study_design_scores_gemma":[0.00009128195,0.0003069246,1.819245e-7,0.0003158278,0.00004657697,0.00001832179,0.000001575174,0.00001573115,0.0001423314,0.000009731763,0.998792,0.0002595355],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000003038759,0.9940183,0.004473508,0.00003540372,0.000702266,0.0005019642,0.00009016258,0.00001735175,0.0001579933],"genre_scores_gemma":[0.00001038359,0.9942349,0.0006699932,0.0004713664,0.0008814965,0.0001370018,0.0002543799,0.00004889382,0.003291639],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.4543562,"threshold_uncertainty_score":0.9380839,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07529093285415142,"score_gpt":0.356312284597205,"score_spread":0.2810213517430535,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}