{"id":"W1827443614","doi":"10.1186/s40360-015-0026-9","title":"A novel nasal powder formulation of glucagon: toxicology studies in animal models","year":2015,"lang":"en","type":"article","venue":"BMC Pharmacology and Toxicology","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lallemand (Canada); Concordia University; Integrity Testing Laboratory (Canada)","funders":"","keywords":"Glucagon; Nasal administration; Medicine; Adverse effect; Insufflation; Hematology; Urinalysis; Hypoglycemia; Pharmacology; Internal medicine; Anesthesia; Endocrinology; Insulin; Urine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007381232,0.0005709148,0.0005349161,0.0005575054,0.0002718758,0.0003118612,0.0005044155,0.0006005573,0.001061293],"category_scores_gemma":[0.0003353012,0.0001692887,0.0005315167,0.0002564496,0.0005051117,0.0006607581,0.0002500377,0.0009108338,0.0002627431],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003334285,"about_ca_system_score_gemma":0.0004213863,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005381051,"about_ca_topic_score_gemma":0.0008086937,"domain_scores_codex":[0.9996891,0.00009640641,0.00002018194,0.00005502756,0.00009916841,0.00004024954],"domain_scores_gemma":[0.9995277,0.00008925083,0.0001745772,0.00005007988,0.00007335441,0.00008498864],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003124764,0.004146132,0.0007010573,0.0004009769,0.0000510257,0.0005967261,0.0001024145,0.0004065044,0.9765626,0.000139895,0.0002244503,0.01354347],"study_design_scores_gemma":[0.0007456647,0.1606189,0.005017469,0.00005171858,0.0002157102,0.002265195,0.0002041386,0.001920274,0.8235213,0.0001211554,0.005290182,0.00002819304],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903623,0.00230729,0.005223906,0.0001852751,0.00009238702,0.0005101359,0.0002349127,0.00006871785,0.001015014],"genre_scores_gemma":[0.9814594,0.004246889,0.01058042,0.0002222809,0.00008900854,0.000491043,0.0006118056,0.00002754436,0.002271557],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001061293,"threshold_uncertainty_score":0.003903627,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3643702975412628,"score_gpt":0.4917092397548541,"score_spread":0.1273389422135913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}