{"id":"W1827444446","doi":"10.1111/j.1471-4159.2011.07601.x","title":"Paradoxical roles of serine racemase and <scp>d</scp>‐serine in the G93A mSOD1 mouse model of amyotrophic lateral sclerosis","year":2011,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Amino Acid Enzymes and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital; Centre for Addiction and Mental Health","funders":"National Institute on Aging; National Institute of Neurological Disorders and Stroke; U.S. Department of Agriculture","keywords":"Serine; Excitotoxicity; Chemistry; NMDA receptor; SOD1; Glutamate receptor; Biochemistry; Amyotrophic lateral sclerosis; Superoxide dismutase; Biology; Cell biology; Receptor; Internal medicine; Oxidative stress; Medicine; Phosphorylation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000289794,0.0008396283,0.0008260919,0.0009196115,0.0002780996,0.0006507954,0.0004408335,0.00126682,0.001191968],"category_scores_gemma":[0.0002377678,0.0003667131,0.0005509306,0.0004108233,0.0009584972,0.0005896506,0.0004133189,0.001769418,0.0004124121],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005946358,"about_ca_system_score_gemma":0.0003968252,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008548989,"about_ca_topic_score_gemma":0.001177677,"domain_scores_codex":[0.9994993,0.00006617863,0.00007520622,0.0001489498,0.0001299158,0.00008051953],"domain_scores_gemma":[0.9994336,0.00003789838,0.0002244363,0.0000504529,0.00004901511,0.0002045706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001025836,0.00009969919,0.000315331,0.00006925054,0.00001776206,0.0003518259,0.00002938336,0.00006406571,0.9964827,0.0002367855,0.00008905813,0.001218166],"study_design_scores_gemma":[0.000232798,0.002507272,0.01699714,0.00004152826,0.0001327663,0.002806347,0.000136161,0.001206521,0.971276,0.0005582509,0.004069923,0.00003517801],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907539,0.003700334,0.002119688,0.0006542961,0.0001113518,0.00005583198,0.00088913,0.0003410544,0.001374426],"genre_scores_gemma":[0.9902651,0.002161313,0.002050214,0.0003273593,0.00004698416,0.0001399166,0.0007868295,0.00007717724,0.004145074],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00126682,"threshold_uncertainty_score":0.004314363,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02495013420078684,"score_gpt":0.2205077857807394,"score_spread":0.1955576515799526,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}