{"id":"W1832186116","doi":"10.1002/stem.1707","title":"YB-1 Transforms Human Mammary Epithelial Cells Through Chromatin Remodeling Leading to the Development of Basal-Like Breast Cancer","year":2014,"lang":"en","type":"article","venue":"Stem Cells","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Biology; Telomerase reverse transcriptase; Chromatin remodeling; Cancer research; Chromatin; BMI1; Telomerase; Epigenetics; Molecular biology; Cell biology; Stem cell; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002066373,0.0002364156,0.0002650016,0.0001937129,0.000131214,0.0002962532,0.0001840348,0.0001691667,0.001221834],"category_scores_gemma":[0.0001174045,0.0001894465,0.0002223775,0.0001724058,0.0001501117,0.000100488,0.000176657,0.000541907,0.0007017085],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002811071,"about_ca_system_score_gemma":0.00028798,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001049987,"about_ca_topic_score_gemma":0.001157943,"domain_scores_codex":[0.999878,0.00001665456,0.00001514667,0.00001954985,0.00004161343,0.00002895554],"domain_scores_gemma":[0.9999065,0.00001594104,0.00002353364,0.00001734451,0.00000799988,0.00002872571],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001006276,0.00004194304,0.0001403734,0.00002022747,0.000003534268,0.00004745481,0.00001737416,0.00003583106,0.9986209,0.0001028382,0.00004883105,0.0008201651],"study_design_scores_gemma":[0.0000414136,0.0003878009,0.002552145,0.000007619216,0.0000138866,0.0003452429,0.00002620619,0.0009425917,0.9905792,0.00006538566,0.005034239,0.000004178117],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887853,0.002732361,0.003680008,0.0002325519,0.00007291316,0.00008817968,0.0009234262,0.0003132852,0.003171986],"genre_scores_gemma":[0.9896926,0.001397445,0.003127008,0.00008457162,0.0000179556,0.00005941403,0.001279709,0.00004920554,0.00429216],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001221834,"threshold_uncertainty_score":0.004087448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02770238063278473,"score_gpt":0.2821469552192426,"score_spread":0.2544445745864579,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}