{"id":"W1834132003","doi":"10.1371/journal.pone.0141493","title":"Urinary Retention, Incontinence, and Dysregulation of Muscarinic Receptors in Male Mice Lacking Mras","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Urinary Bladder and Prostate Research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Vancouver Hospital and Health Sciences Centre","funders":"Canadian Institutes of Health Research","keywords":"Muscarinic acetylcholine receptor; Carbachol; Endocrinology; Internal medicine; MRAS; Overactive bladder; Urinary bladder; Biology; Downregulation and upregulation; Agonist; Medicine; Receptor; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002331614,0.0008932027,0.0005108601,0.001121695,0.0003594902,0.0004381024,0.0004167632,0.0007674927,0.002620768],"category_scores_gemma":[0.0001857714,0.0004529158,0.00055548,0.0002224906,0.0005612427,0.0005030804,0.000412818,0.001212394,0.0005587107],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001965972,"about_ca_system_score_gemma":0.0001912877,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004517563,"about_ca_topic_score_gemma":0.0007856914,"domain_scores_codex":[0.9996197,0.00005228017,0.00004432562,0.00009881169,0.0001197987,0.00006503203],"domain_scores_gemma":[0.999455,0.00003896432,0.0002905104,0.0000416719,0.00003151608,0.0001422264],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001906129,0.00005649869,0.001158504,0.00004207886,0.00001729499,0.000438021,0.00005022722,0.00003078179,0.9962315,0.0001238589,0.00005694605,0.001603707],"study_design_scores_gemma":[0.000061862,0.001677701,0.06743657,0.00005094034,0.0001441445,0.01210465,0.0002541291,0.0006155232,0.9129501,0.0002421335,0.004420145,0.00004219483],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920184,0.001805254,0.003781149,0.000259949,0.00005837283,0.00002989977,0.0007907581,0.0002145683,0.001041442],"genre_scores_gemma":[0.9891779,0.001722631,0.003008286,0.0001591371,0.00004827225,0.00007181476,0.0006714263,0.00009859718,0.005042041],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002620768,"threshold_uncertainty_score":0.008767307,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1060841190487796,"score_gpt":0.2957544794750181,"score_spread":0.1896703604262385,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}