{"id":"W1834977033","doi":"10.4187/respcare.05501201","title":"The CFC to HFA Transition and Its Impact on Pulmonary Drug Development","year":2005,"lang":"en","type":"article","venue":"Respiratory Care","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Montreal Protocol; SAFER; Intensive care medicine; Pharmacology; Ozone layer","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002195713,0.0001732142,0.0001605858,0.0001236413,0.0003522448,0.00003058575,0.00006451368,0.00007570651,0.00006205701],"category_scores_gemma":[0.00002625722,0.0001079612,0.00007686894,0.0001417653,0.00002680003,0.00007393923,0.00002004297,0.0001811702,0.0002824885],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000276671,"about_ca_system_score_gemma":0.0002399794,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001158103,"about_ca_topic_score_gemma":0.00001444697,"domain_scores_codex":[0.9988827,0.00007453698,0.0002393267,0.0002426723,0.0003216661,0.0002391108],"domain_scores_gemma":[0.999288,0.00004970992,0.0000395361,0.0002036771,0.0001733976,0.0002456901],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002054676,0.0002756365,0.002708104,0.0003346876,0.0001839177,0.0002981584,0.0215498,0.001822633,0.08799066,0.0002453954,0.01462648,0.8679098],"study_design_scores_gemma":[0.001151901,0.000363255,0.03809067,0.0002358569,0.00004356788,0.00003638476,0.00237752,0.0001152686,0.1329996,0.000001314342,0.8242297,0.0003549386],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905744,0.003173247,0.000006897217,0.001280381,0.00009566093,0.0004817802,0.000009356856,0.00006477792,0.004313519],"genre_scores_gemma":[0.9910164,0.00002214693,0.00003565906,0.00799612,0.0003608056,0.00003095286,0.000009615258,0.00002388983,0.0005044497],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8675549,"threshold_uncertainty_score":0.4402531,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01318883875219732,"score_gpt":0.293172250806669,"score_spread":0.2799834120544717,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}