{"id":"W1837459431","doi":"10.1139/bcb-2014-0136","title":"Proposed trial: safety and efficacy of resveratrol for the treatment of non-alcoholic fatty liver disease (NAFLD) and associated insulin resistance in adolescents who are overweight or obese adolescents — rationale and protocol","year":2015,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Research Manitoba; St. Boniface Hospital; Manitoba Health; Winnipeg Regional Health Authority; University of Manitoba; Children's Hospital Research Institute of Manitoba; CARE Canada","funders":"DSM Nutritional Products; Health Canada","keywords":"Medicine; Fatty liver; Overweight; Tolerability; Insulin resistance; Population; Internal medicine; Placebo; Type 2 diabetes; Diabetes mellitus; Resveratrol; Randomized controlled trial; Obesity; Disease; Adverse effect; Endocrinology; Pharmacology; Environmental health","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009100212,0.003243356,0.00386291,0.001187342,0.001727873,0.002763363,0.002550172,0.006241147,0.04083806],"category_scores_gemma":[0.01218786,0.001267891,0.003536533,0.001032933,0.002196045,0.002175049,0.001326317,0.004801417,0.008552644],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001915193,"about_ca_system_score_gemma":0.007290775,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00102154,"about_ca_topic_score_gemma":0.002484721,"domain_scores_codex":[0.9945746,0.003445571,0.0005893802,0.0004734047,0.0004675401,0.0004495663],"domain_scores_gemma":[0.9962064,0.0009239125,0.0009484251,0.0003447585,0.0006818697,0.0008945964],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"not_applicable","study_design_scores_codex":[0.9019634,0.01188167,0.001236678,0.02172352,0.001720784,0.0002305705,0.0002020258,0.0008433372,0.00290754,0.002058845,0.01409318,0.04113842],"study_design_scores_gemma":[0.9277791,0.04162461,0.001821627,0.002382787,0.001256269,0.00009615676,0.00006687565,0.0005015863,0.0007487379,0.001037684,0.02262292,0.00006151978],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.0268249,0.00507886,0.001958949,0.002607252,0.001302231,0.9470381,0.007645635,0.0002507208,0.00729336],"genre_scores_gemma":[0.03583624,0.003668867,0.006377807,0.002665395,0.0008192386,0.9429349,0.0025702,0.00003668174,0.005090808],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.04083806,"threshold_uncertainty_score":0.1366169,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02665318479334629,"score_gpt":0.2991993332628018,"score_spread":0.2725461484694556,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}