{"id":"W1839851754","doi":"10.1038/emboj.2010.311","title":"Interplay between lysine methylation and Cdk phosphorylation in growth control by the retinoblastoma protein","year":2010,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":107,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Medical Research Council; Canadian Institutes of Health Research; Knut och Alice Wallenbergs Stiftelse; Karolinska Institutet; Stiftelsen för Strategisk Forskning; Cancer Research UK; Ontario Genomics Institute; National Institute for Health and Care Research; Ontario Genomics; Genome Canada; GlaxoSmithKline; Ontario Innovation Trust; Wellcome Trust","keywords":"Biology; Methylation; Lysine; Phosphorylation; Retinoblastoma protein; Retinoblastoma; Cyclin-dependent kinase; Genetics; Cell biology; Biochemistry; Cell cycle; DNA; Gene; Amino acid","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003730599,0.0003048881,0.0003284549,0.0002547243,0.0003947886,0.000830257,0.0004809283,0.0003337634,0.001818707],"category_scores_gemma":[0.0004300686,0.0002975315,0.0002174704,0.0001966838,0.0005767038,0.0007448636,0.0005915776,0.0004843338,0.0007720639],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008325966,"about_ca_system_score_gemma":0.0004907329,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001457987,"about_ca_topic_score_gemma":0.003571456,"domain_scores_codex":[0.9998395,0.00002590902,0.00001037642,0.00004049938,0.00003231409,0.00005141032],"domain_scores_gemma":[0.9998435,0.00003546989,0.00003727504,0.00002238202,0.00002157316,0.0000398098],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001149431,0.00003796187,0.002697099,0.00008751825,0.00002773237,0.0002510602,0.00007037952,0.0009726235,0.9806621,0.004263616,0.0002123493,0.009568137],"study_design_scores_gemma":[0.00009718733,0.0001814895,0.02454578,0.00002014887,0.00005439749,0.000458581,0.0001665753,0.008533673,0.9577098,0.003644323,0.004548455,0.00003970075],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9754676,0.01036465,0.005909861,0.0009094711,0.000115791,0.0000134211,0.0001945084,0.0001257449,0.006898973],"genre_scores_gemma":[0.9960542,0.001530112,0.0006181459,0.00003941783,0.00001765463,0.000003764787,0.00007017887,0.00001803682,0.001648406],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001818707,"threshold_uncertainty_score":0.006084204,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004620926438443525,"score_gpt":0.2513802433227828,"score_spread":0.2467593168843393,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}