{"id":"W1840476766","doi":"10.1016/j.str.2015.08.014","title":"Structure of AcrH–AopB Chaperone-Translocator Complex Reveals a Role for Membrane Hairpins in Type III Secretion System Translocon Assembly","year":2015,"lang":"en","type":"article","venue":"Structure","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":false,"ca_institutions":"Trinity Western University; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; State Key Laboratory of Bioreactor Engineering","keywords":"Translocon; Chaperone (clinical); Biology; Effector; Secretion; Cell biology; Transmembrane protein; Biophysics; Biochemistry; Membrane protein; Membrane; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015932,0.0002574817,0.0004413183,0.00008592838,0.00006272199,0.00002104603,0.0002852939,0.0003115776,0.00001681019],"category_scores_gemma":[0.00008519678,0.0002237481,0.0000932635,0.0001892,0.0001031762,0.0000109991,0.00005787996,0.0001451115,6.569369e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006523336,"about_ca_system_score_gemma":0.0001768392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008155727,"about_ca_topic_score_gemma":0.000753138,"domain_scores_codex":[0.9984629,0.0001082514,0.0003567838,0.0004268924,0.0002524203,0.0003927218],"domain_scores_gemma":[0.9990355,0.0000141862,0.0001249323,0.0003742543,0.0003158134,0.0001352504],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008247103,0.00001359691,0.0004447882,0.00040685,0.00009566661,0.000001687481,0.0005831225,0.0001430655,0.9964861,0.0002171302,0.0003786164,0.0004046694],"study_design_scores_gemma":[0.004984809,0.0012053,0.008959896,0.0001406772,0.00006294383,0.00003456917,0.002064872,0.0006807759,0.9749559,0.0003376436,0.006080829,0.0004917402],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965577,0.0008801952,0.0003586168,0.0001682805,0.0002199055,0.0008987443,0.0007728087,0.00002042372,0.0001233791],"genre_scores_gemma":[0.9977064,0.00003644619,0.001103494,0.00004466116,0.0002487993,0.00002171714,0.0007431631,0.00003759863,0.00005771857],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02153015,"threshold_uncertainty_score":0.9124181,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02187156614070256,"score_gpt":0.2893993588228675,"score_spread":0.2675277926821649,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}