{"id":"W1844115570","doi":"10.4049/jimmunol.169.5.2611","title":"Lipopolysaccharide Signals an Endothelial Apoptosis Pathway Through TNF Receptor-Associated Factor 6-Mediated Activation of c-Jun NH2-Terminal Kinase","year":2002,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":107,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"","keywords":"Tumor necrosis factor alpha; Cancer research; Apoptosis; Kinase; Lipopolysaccharide; Chemistry; Terminal (telecommunication); Signal transduction; Cell biology; Medicine; Biology; Internal medicine; Biochemistry; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005857263,0.0002520896,0.0004327408,0.0001128063,0.0001279635,0.00001628116,0.0006304549,0.0003499838,0.0003763803],"category_scores_gemma":[0.0006747832,0.0001889705,0.0002072935,0.0001480262,0.000249953,0.00003532624,0.00009594339,0.0004080879,0.0000186994],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006048911,"about_ca_system_score_gemma":0.0001104919,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007662347,"about_ca_topic_score_gemma":0.000007641848,"domain_scores_codex":[0.9976961,0.0006865241,0.0007769631,0.0001962668,0.000282249,0.0003619077],"domain_scores_gemma":[0.997682,0.0001790106,0.00123604,0.0004142212,0.0004226781,0.00006608073],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000563485,0.0003715953,0.0001337443,0.00000717871,0.0003565309,0.000003717899,0.0008896288,0.00004961461,0.9944701,0.00002334987,0.0003374202,0.002793697],"study_design_scores_gemma":[0.001328138,0.002442763,0.0002527802,0.00005548064,0.00006066021,0.00007604624,0.0003474946,0.00003045649,0.9936923,0.00009951481,0.001424737,0.0001896539],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997283,0.0008681664,0.0007873304,0.000270062,0.0004408965,0.0001490873,0.0001029841,0.0000134454,0.00008498455],"genre_scores_gemma":[0.9982266,0.0007378156,0.0003003083,0.0002018923,0.0003088467,0.00000419892,0.00004239236,0.00003956742,0.000138422],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002604043,"threshold_uncertainty_score":0.7705995,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02505888985602223,"score_gpt":0.2466142812734173,"score_spread":0.2215553914173951,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}