{"id":"W1844975765","doi":"10.1111/j.1365-2559.2010.03554.x","title":"Genomic and immunophenotypical differences between hepatocellular carcinoma with and without cirrhosis","year":2010,"lang":"en","type":"article","venue":"Histopathology","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Calgary Laboratory Services; University of Calgary","funders":"","keywords":"Hepatocellular carcinoma; Cyclin D1; Cirrhosis; Cancer research; Pathogenesis; Immunohistochemistry; Biology; Wnt signaling pathway; Pathology; Carcinoma; Tissue microarray; Retinoblastoma; Cell cycle; Medicine; Cancer; Gene; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001335994,0.0001531494,0.0001510192,0.001172743,0.0001892462,0.0002427912,0.00009322172,0.0002095088,0.00291228],"category_scores_gemma":[0.0006700037,0.00007525869,0.0001206087,0.0004100763,0.0002262009,0.000140864,0.0002138323,0.0001052568,0.0003154568],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001430396,"about_ca_system_score_gemma":0.0001095495,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005933761,"about_ca_topic_score_gemma":0.000630184,"domain_scores_codex":[0.9998432,0.00002715543,0.00001636936,0.00004016099,0.00002849253,0.00004459625],"domain_scores_gemma":[0.999479,0.0001588913,0.0001495503,0.00003643076,0.00006065256,0.0001154918],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0014637,0.00005511109,0.8982576,0.00007006372,0.00006874677,0.002067168,0.0001751428,0.00008652985,0.09079175,0.0001258684,0.0001075367,0.006730744],"study_design_scores_gemma":[0.000008636236,0.0001476855,0.9905156,0.000004418566,0.00002377071,0.005022528,0.0002266664,0.0001385725,0.003529017,0.00007463751,0.0003044271,0.00000404741],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989467,0.0001826493,0.0001880668,0.00001189003,0.000002951992,0.000005750661,0.0001283062,0.000005885172,0.0005277627],"genre_scores_gemma":[0.9994459,0.00007049651,0.00008923858,0.000009201035,0.000006957689,0.000006941789,0.0002125386,0.00000256807,0.000156206],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00291228,"threshold_uncertainty_score":0.009742558,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03258372257116898,"score_gpt":0.2251687225098723,"score_spread":0.1925849999387033,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}