{"id":"W1845127980","doi":"10.1002/cncr.29544","title":"Phase 1 adaptive dose‐finding study of neoadjuvant gemcitabine combined with radiation therapy for patients with high‐risk extremity and trunk soft tissue sarcoma","year":2015,"lang":"en","type":"article","venue":"Cancer","topic":"Sarcoma Diagnosis and Treatment","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"National Cancer Institute; Eli Lilly and Company","keywords":"Medicine; Gemcitabine; Toxicity; Soft tissue sarcoma; Radiation therapy; Internal medicine; Oncology; Sarcoma; Surgery; Soft tissue; Radiology; Chemotherapy; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001017935,0.0009524699,0.001334653,0.0002983874,0.0002438705,0.0004316984,0.0006521524,0.0004275756,0.001380589],"category_scores_gemma":[0.0007226607,0.0003348118,0.0006029955,0.0003219944,0.000637422,0.0003674928,0.0002715862,0.001193379,0.0002531361],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007201754,"about_ca_system_score_gemma":0.001299741,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007346604,"about_ca_topic_score_gemma":0.001780398,"domain_scores_codex":[0.999669,0.0001761668,0.0000174056,0.0000582348,0.00004174582,0.00003755614],"domain_scores_gemma":[0.9997044,0.00006535969,0.0000776121,0.0000354303,0.00001933879,0.00009792469],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.4399583,0.1180144,0.05019385,0.0009288914,0.002045964,0.000451475,0.0008292749,0.02277146,0.1202407,0.0003455457,0.001875072,0.2423451],"study_design_scores_gemma":[0.2061083,0.7229704,0.04339503,0.00004091515,0.0007841764,0.0006031119,0.0001259498,0.008914552,0.0138812,0.0002565463,0.002874603,0.0000451246],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985544,0.0003431519,0.000359338,0.00005934083,0.00001313256,0.0003580946,0.00005357945,0.0000169988,0.0002419893],"genre_scores_gemma":[0.9957569,0.000457112,0.002163717,0.0001392849,0.00002817621,0.0007549362,0.0003028668,0.0000103088,0.0003867605],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001380589,"threshold_uncertainty_score":0.005383372,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0347248114181832,"score_gpt":0.3133005594967833,"score_spread":0.2785757480786001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}