{"id":"W1847270645","doi":"10.4049/jimmunol.172.6.3422","title":"Distinct Profiles of Human B Cell Effector Cytokines: A Role in Immune Regulation?","year":2004,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":359,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Lymphotoxin; Cytokine; Immune system; Biology; Proinflammatory cytokine; Cell biology; Autocrine signalling; CD40; B cell; Context (archaeology); Effector; Immunology; T cell; Receptor; Inflammation; Cytotoxic T cell; Antibody; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009410952,0.0002672154,0.0007803632,0.0003750512,0.0001909169,0.000006397492,0.0008422975,0.0003803697,0.000374341],"category_scores_gemma":[0.0001064966,0.0001768938,0.0002212032,0.0003028213,0.0008743347,0.0001234682,0.0001829455,0.0008996262,0.0001570622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000109462,"about_ca_system_score_gemma":0.0001580495,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004983951,"about_ca_topic_score_gemma":0.00006665915,"domain_scores_codex":[0.9973254,0.0007666407,0.001221933,0.0001646933,0.00006408432,0.0004573076],"domain_scores_gemma":[0.9977868,0.000373168,0.001132285,0.0004892494,0.0002037993,0.00001467775],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009450459,0.0005605006,0.001887946,0.00002656736,0.0002561359,0.00001298183,0.001329699,0.00006118619,0.99356,0.0007687495,0.00006374631,0.0005275077],"study_design_scores_gemma":[0.005689031,0.001812689,0.05538265,0.0001218313,0.0001084594,0.0007223656,0.0009723115,4.694701e-7,0.9314416,0.002572905,0.001000889,0.0001747775],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9795978,0.01829205,0.00006639422,0.0003660634,0.0006910547,0.00026509,0.000009653321,0.00001927243,0.0006926493],"genre_scores_gemma":[0.9989591,0.000259049,0.00005677743,0.00002439482,0.00004650757,0.000007545012,0.00002362072,0.00002558266,0.000597416],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06211831,"threshold_uncertainty_score":0.7213518,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006804106547182589,"score_gpt":0.220788889959466,"score_spread":0.2139847834122834,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}