{"id":"W1847360632","doi":"10.1139/v02-072","title":"Medium-size cyclophanes. Part 60<sup>1</sup>: Synthesis and conformational studies of 9-substituted [3.3]metacyclophane-2,11-diones and conversion to the corresponding [3.3]metacyclophanes","year":2002,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Synthesis and Properties of Aromatic Compounds","field":"Chemistry","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chemistry; Cyclophane; Dimethylformamide; Sodium hydride; Selectivity; Hydride; Medicinal chemistry; Crystallography; Stereochemistry; Crystal structure; Organic chemistry; Metal; Solvent","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006975613,0.0001460211,0.0001001948,0.00006333837,0.000107271,0.0001016909,0.0001244302,0.0001098205,0.002617823],"category_scores_gemma":[0.0001260034,0.00005173025,0.0001058575,0.00009300587,0.0001228857,0.0001648899,0.0000816445,0.0002041702,0.000305667],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001332216,"about_ca_system_score_gemma":0.0001025837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000363368,"about_ca_topic_score_gemma":0.0005308558,"domain_scores_codex":[0.999962,0.000006487774,0.000002822043,0.000008763003,0.000008635312,0.00001134641],"domain_scores_gemma":[0.999947,0.00001482581,0.00001388434,0.000006572495,0.000005050392,0.00001285081],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001845675,0.00001636143,0.0001519166,0.00005079045,0.000003511212,0.0000886703,0.00001855517,0.0001269671,0.9965043,0.0002277145,0.00004411598,0.002582557],"study_design_scores_gemma":[0.00002101237,0.000601195,0.002416746,0.000005213311,0.000009626212,0.0003312424,0.00001730294,0.0001968488,0.9931816,0.00006691844,0.003148431,0.000003801608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940733,0.001244642,0.001273572,0.00002978158,0.00001474014,0.00001533783,0.0001954269,0.00001542651,0.003137862],"genre_scores_gemma":[0.9963762,0.0005767336,0.0013859,0.00001680881,0.00000378408,0.00001063851,0.0002623254,0.000007972882,0.001359542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002617823,"threshold_uncertainty_score":0.008757532,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02581147996209962,"score_gpt":0.2176911701807759,"score_spread":0.1918796902186763,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}