{"id":"W1848220679","doi":"10.1186/1471-2407-3-21","title":"Therapeutic limitations in tumor-specific CD8+ memory T cell engraftment","year":2003,"lang":"en","type":"article","venue":"BMC Cancer","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Institute of Allergy and Infectious Diseases; U.S. Department of Defense","keywords":"CTL*; Adoptive cell transfer; Cytotoxic T cell; CD8; Immunotherapy; Immunology; Cancer research; Ex vivo; Medicine; T cell; Cell therapy; In vivo; Biology; Immune system; In vitro; Stem cell; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001550284,0.0004917488,0.0004515346,0.0002715455,0.000141488,0.0007614016,0.0005098768,0.0008843674,0.00164514],"category_scores_gemma":[0.0009428774,0.0001187307,0.0002950702,0.0001432615,0.0005754335,0.0006699814,0.0003571345,0.001686642,0.0004475312],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004648163,"about_ca_system_score_gemma":0.0003022003,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000124665,"about_ca_topic_score_gemma":0.000117015,"domain_scores_codex":[0.9994853,0.0001753214,0.00004617402,0.00007018734,0.0001321039,0.00009083057],"domain_scores_gemma":[0.9991971,0.0004884937,0.0001418656,0.00007248032,0.00004906729,0.00005102245],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009175268,0.0009349089,0.002211612,0.001694764,0.0001145038,0.0007659755,0.0001987613,0.003625478,0.8632016,0.007064847,0.001875796,0.1173942],"study_design_scores_gemma":[0.0004123766,0.0165689,0.006407068,0.0005235044,0.0005177102,0.01498365,0.0002002209,0.01010568,0.8723387,0.007020656,0.07088505,0.00003656614],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8800891,0.06580379,0.03856634,0.00395846,0.0004274345,0.0003237006,0.000205469,0.0004553257,0.01017044],"genre_scores_gemma":[0.9819666,0.009835921,0.005734542,0.0005094548,0.0001918214,0.0002182058,0.0001588974,0.0000330496,0.001351397],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00164514,"threshold_uncertainty_score":0.008198798,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1312898304289417,"score_gpt":0.3417320469958789,"score_spread":0.2104422165669372,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}