{"id":"W185373952","doi":"10.1096/fasebj.21.5.a196","title":"Glucocorticoids enhance aryl hydrocarbon receptor expression and function in mouse hepatoma cells","year":2007,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Aryl hydrocarbon receptor; Glucocorticoid receptor; Internal medicine; Endocrinology; Aryl hydrocarbon receptor nuclear translocator; Antiglucocorticoid; Pregnane X receptor; Receptor; Transfection; Glucocorticoid; Transcription factor; Luciferase; Biology; Chemistry; Response element; Endocrine system; Nuclear receptor; Gene expression; Cell culture; Hormone; Promoter; Biochemistry; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003522857,0.0005817958,0.0003438313,0.0008942283,0.0002244224,0.0004434765,0.0002372488,0.0002803235,0.004038657],"category_scores_gemma":[0.0001966524,0.0002829625,0.0005322828,0.0003971571,0.000232674,0.000285583,0.0003025465,0.001020753,0.003340831],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004600502,"about_ca_system_score_gemma":0.0001842777,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001442341,"about_ca_topic_score_gemma":0.002265161,"domain_scores_codex":[0.9994887,0.0001045002,0.00005255625,0.00008885465,0.0001622205,0.0001030994],"domain_scores_gemma":[0.9995133,0.0001268625,0.00007266018,0.0001052722,0.0000774896,0.0001044438],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001397229,0.00004547316,0.00008652174,0.00001792268,0.000003451509,0.00004002272,0.00001862222,0.00002157242,0.9987535,0.00007118408,0.00008234385,0.0007195226],"study_design_scores_gemma":[0.00004872732,0.0005191745,0.004547148,0.000007373266,0.00001749487,0.0001888717,0.00003180384,0.0002816352,0.9883488,0.00004705905,0.005955099,0.000006741492],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9539505,0.00832868,0.0131771,0.0007235713,0.0003859389,0.0001878806,0.005283797,0.001338687,0.01662387],"genre_scores_gemma":[0.9424588,0.004370637,0.009381642,0.0003092302,0.0001328312,0.000193792,0.005518271,0.0002801498,0.03735467],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004038657,"threshold_uncertainty_score":0.01351064,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004076803571270006,"score_gpt":0.2181129554392249,"score_spread":0.2140361518679549,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}