{"id":"W1855228290","doi":"10.1002/jor.23059","title":"Synergistic effect of exogeneous and endogeneous electrostimulation on osteogenic differentiation of human mesenchymal stem cells seeded on silk scaffolds","year":2015,"lang":"en","type":"article","venue":"Journal of Orthopaedic Research®","topic":"Bone Tissue Engineering Materials","field":"Engineering","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; National Institute of Arthritis and Musculoskeletal and Skin Diseases; McMaster University","keywords":"Mesenchymal stem cell; Alkaline phosphatase; Endogeny; Cell biology; Chemistry; Bone sialoprotein; Osteopontin; Stem cell; Downregulation and upregulation; Glibenclamide; Osteocalcin; Immunology; Biology; Endocrinology; Biochemistry; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009216493,0.0002133688,0.0001916521,0.0001105502,0.00005553022,0.0001809401,0.00007490828,0.0001440983,0.00049691],"category_scores_gemma":[0.00009705903,0.00008786472,0.0001357999,0.00007456426,0.0001465193,0.0001137133,0.0001815856,0.0001220755,0.00006945047],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006288554,"about_ca_system_score_gemma":0.00008251455,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001523379,"about_ca_topic_score_gemma":0.0005142591,"domain_scores_codex":[0.999917,0.00001605495,0.000009476067,0.00001643143,0.00002392992,0.0000170551],"domain_scores_gemma":[0.9999286,0.00002827208,0.00001506169,0.00000552032,0.000008073111,0.00001452876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001119295,0.0000113653,0.000119629,0.00002213777,0.000003355638,0.00002366576,0.000008793998,0.00004005583,0.9988023,0.00001079184,0.000005491777,0.000840484],"study_design_scores_gemma":[0.00001246067,0.0002549799,0.003497714,0.000003102251,0.00001773766,0.00006684341,0.00002271554,0.0003406152,0.9952787,0.00001280623,0.0004894038,0.000002952394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982091,0.00055346,0.0006559654,0.00001444632,0.00001113916,0.000007731069,0.00003149727,0.000007389452,0.0005091809],"genre_scores_gemma":[0.9980385,0.0005561659,0.000895453,0.00001677073,0.0000095151,0.00001588853,0.00003130521,0.000003634328,0.0004328474],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00049691,"threshold_uncertainty_score":0.001662374,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03767959158979211,"score_gpt":0.2931706871638535,"score_spread":0.2554910955740614,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}