{"id":"W1856115540","doi":"10.1093/neuonc/nov143","title":"Comparative genomic and genetic analysis of glioblastoma-derived brain tumor-initiating cells and their parent tumors","year":2015,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of Calgary","funders":"Terry Fox Research Institute; Consorzio per la Ricerca Sanitaria; Health Research Board","keywords":"Biology; Copy-number variation; Gene; Computational biology; Genetics; Single-nucleotide polymorphism; Glioma; Subtyping; Glioblastoma; SNP; Cancer research; Genome; Genotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000142409,0.0001583879,0.0001661256,0.0007632559,0.0001418093,0.0001901738,0.0001393759,0.0001433779,0.0005914183],"category_scores_gemma":[0.0002757625,0.00007894765,0.0001993004,0.000559093,0.0001092993,0.00006630369,0.0001435904,0.0002110872,0.0001759374],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002420006,"about_ca_system_score_gemma":0.0001642374,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001544515,"about_ca_topic_score_gemma":0.001629838,"domain_scores_codex":[0.9998627,0.00001461842,0.00001400038,0.00003585208,0.00005245941,0.00002044888],"domain_scores_gemma":[0.9998172,0.00004450603,0.00004931445,0.00002693513,0.00003777996,0.0000242605],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001389645,0.00003263207,0.007206536,0.00002774344,0.00003055791,0.0001632214,0.00004855195,0.00014207,0.9893479,0.00008275601,0.00003189908,0.002747203],"study_design_scores_gemma":[0.00003554471,0.001288368,0.4591187,0.00001337571,0.0002958783,0.002809678,0.0001950297,0.002882304,0.5282986,0.0002457715,0.004796447,0.00002035011],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953669,0.0002958358,0.002398327,0.000008234196,0.000004149921,0.00002682649,0.00128829,0.00003614412,0.0005752056],"genre_scores_gemma":[0.9875342,0.000526786,0.004534862,0.00002577008,0.000005197632,0.00008111203,0.006817293,0.00002127069,0.0004536011],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001544515,"threshold_uncertainty_score":0.00307107,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04093286239203268,"score_gpt":0.3052093690573074,"score_spread":0.2642765066652747,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}