{"id":"W1856227328","doi":"10.1016/s0076-6879(02)53067-6","title":"Transgenic Shuttle Vector Assays for Determining Genetic Differences in Oxidative B Cell Mutagenesis in Vivo","year":2002,"lang":"en","type":"article","venue":"Methods in enzymology on CD-ROM/Methods in enzymology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"University of Texas Health Science Center at San Antonio; National Institutes of Health; University of Victoria","keywords":"Mutagenesis; Carcinogenesis; In vivo; Transgene; Biology; Shuttle vector; Oxidative stress; Oxidative phosphorylation; Mutation; Congenic; Cell; Genetics; Molecular biology; Cell biology; Gene; Biochemistry; Vector (molecular biology); Recombinant DNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.006260448,0.001174564,0.003041854,0.002776341,0.0002128072,0.00002397156,0.001561853,0.003096439,0.002605457],"category_scores_gemma":[0.002199507,0.00117807,0.0004243729,0.001510297,0.001531399,0.0001539776,0.0003382087,0.002591283,0.0001358608],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004706862,"about_ca_system_score_gemma":0.0001443489,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006942223,"about_ca_topic_score_gemma":0.00400979,"domain_scores_codex":[0.9718184,0.02058675,0.002550568,0.002327401,0.0001034285,0.002613437],"domain_scores_gemma":[0.9821895,0.01583902,0.0006356475,0.001147867,0.00009152475,0.0000963954],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007136258,0.001704041,0.02665741,0.00009572854,0.0001276847,0.0002761001,0.003723204,0.0001672213,0.9237785,0.0005982334,0.0001712151,0.04198709],"study_design_scores_gemma":[0.01540628,0.004389991,0.1720763,0.0002030484,0.0001592464,0.000589335,0.001670106,0.000595678,0.7866938,0.01032491,0.005747769,0.002143577],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9541771,0.007804709,0.0302078,0.0003650667,0.003680285,0.001625871,0.0000673883,0.000127783,0.001944015],"genre_scores_gemma":[0.6376573,0.0006152981,0.3583147,0.0004796946,0.00006525355,0.001016802,0.0000205702,0.0001114347,0.001718956],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3281069,"threshold_uncertainty_score":0.9997098,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06326191314289177,"score_gpt":0.3464311344071106,"score_spread":0.2831692212642188,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}