{"id":"W1857640949","doi":"10.3978/j.issn.2305-5839.2015.10.31","title":"Muscle pathology, limb strength, walking gait, respiratory function and neurological impairment establish disease progression in the p.N155K canine model of X-linked myotubular myopathy.","year":2015,"lang":"en","type":"article","venue":"PubMed","topic":"Neurological diseases and metabolism","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Heart, Lung, and Blood Institute","keywords":"Medicine; Skeletal muscle; Muscle weakness; Congenital myopathy; Internal medicine; Pathology; Muscle biopsy; Biopsy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008979619,0.0002056093,0.0002494946,0.0001116225,0.00009542028,0.00005663998,0.0003115138,0.00009673507,0.000003794731],"category_scores_gemma":[0.001895377,0.0001289233,0.0000799409,0.0002976416,0.0002546217,0.0002087286,0.0002269615,0.0003140918,0.000001149143],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001547564,"about_ca_system_score_gemma":0.00005622937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005279256,"about_ca_topic_score_gemma":0.000002865973,"domain_scores_codex":[0.9972404,0.0007857502,0.0003606631,0.0006221875,0.0004718757,0.0005190963],"domain_scores_gemma":[0.9987827,0.000197327,0.0001633023,0.0003839484,0.00004658012,0.0004261661],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.01336718,0.01182666,0.259542,0.0003245777,0.00001860652,0.003168273,0.001618995,0.008773838,0.06685232,0.01386392,0.002154803,0.6184888],"study_design_scores_gemma":[0.001275868,0.0004692036,0.9875149,0.000005467336,0.00004563334,0.000005610128,0.00003915358,0.006134683,0.0001405183,0.003495507,0.0007202727,0.0001531687],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969274,0.0007257703,0.00003303267,0.0006606585,0.0002389815,0.001153649,0.00004419365,0.00007128859,0.000145012],"genre_scores_gemma":[0.9940138,0.00009331837,0.00001992897,0.004790203,0.00009731486,0.0009539406,0.000004100387,0.00001566808,0.00001165221],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.727973,"threshold_uncertainty_score":0.5257338,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06116513902631296,"score_gpt":0.257699712365687,"score_spread":0.196534573339374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}