{"id":"W1859087985","doi":"10.1371/journal.pone.0141441","title":"Bacterial Species-Specific Activity of a Fluoroquinolone against Two Closely Related Pasteurellaceae with Similar MICs: Differential In Vitro Inoculum Effects and In Vivo Efficacies","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Antibiotics Pharmacokinetics and Efficacy","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vétoquinol (Canada)","funders":"","keywords":"Pasteurella multocida; Microbiology; Biology; Pasteurellaceae; In vivo; Pasteurellosis; In vitro; Bacteria; Antimicrobial; Antibiotics; Pasteurella","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004065444,0.0004724451,0.0005315317,0.0002572754,0.0001155899,0.0002843558,0.0002258768,0.000605567,0.0005147554],"category_scores_gemma":[0.0006855312,0.0001755664,0.000315717,0.0001744204,0.0002353157,0.0003199342,0.0002468005,0.000519005,0.0001169274],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002129154,"about_ca_system_score_gemma":0.0001619544,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005714774,"about_ca_topic_score_gemma":0.000596329,"domain_scores_codex":[0.999559,0.0001296899,0.00004598178,0.0000854399,0.0001003333,0.00007950913],"domain_scores_gemma":[0.9995531,0.0001498945,0.0001162966,0.0000377176,0.00008241284,0.00006051389],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001401354,0.00005200644,0.0004522269,0.00004902097,0.00000845534,0.00002254037,0.00002181267,0.00004742236,0.9983196,0.000006863237,0.000005050884,0.0008748315],"study_design_scores_gemma":[0.00003895857,0.005775208,0.02510397,0.00001189171,0.00005674739,0.0004730057,0.00005557645,0.0004434714,0.967456,0.00002291781,0.0005500734,0.00001207308],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975228,0.001375676,0.0006762626,0.00003742686,0.00001019435,0.00002925565,0.0001143265,0.00001213749,0.0002220453],"genre_scores_gemma":[0.9968264,0.000634808,0.001931343,0.00003380738,0.00001284736,0.00002957649,0.0002629731,0.000005228522,0.0002630257],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000605567,"threshold_uncertainty_score":0.002150059,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03232113305007502,"score_gpt":0.2356870808183716,"score_spread":0.2033659477682966,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}