{"id":"W1862652544","doi":"10.1039/c5cc02227d","title":"Experimental and mechanistic analysis of the palladium-catalyzed oxidative C8-selective C–H homocoupling of quinoline N-oxides","year":2015,"lang":"en","type":"article","venue":"Chemical Communications","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"Discovery Centre","funders":"National Institute of General Medical Sciences; National Institute on Minority Health and Health Disparities; Welch Foundation","keywords":"Quinoline; Palladium; Catalysis; Chemistry; Oxidative phosphorylation; Combinatorial chemistry; Medicinal chemistry; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002494256,0.0001277195,0.0003331251,0.00009480533,0.00008571616,0.00001114265,0.0006629021,0.00008841941,0.00008855716],"category_scores_gemma":[0.001026966,0.000110465,0.000143604,0.000911779,0.000508711,0.00005616421,0.0006109666,0.0001752943,0.000001127554],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001333708,"about_ca_system_score_gemma":0.0001051674,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008366472,"about_ca_topic_score_gemma":0.00001033477,"domain_scores_codex":[0.9989665,0.00005534325,0.0004322199,0.0001938931,0.0002405754,0.00011144],"domain_scores_gemma":[0.9972811,0.0006444256,0.0003137461,0.001292926,0.00037984,0.00008794408],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002738215,0.0001928673,0.00134199,0.00001869149,0.0004528455,4.405883e-8,0.0009999498,0.00006493651,0.9928222,0.003962179,0.00004216487,0.00007477317],"study_design_scores_gemma":[0.0003914788,0.000006020647,0.0003749942,0.00002575461,0.0006182157,0.000002546189,0.001096051,0.00858705,0.9875735,0.001100345,0.0001172642,0.0001067718],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877938,0.001420466,0.006414801,0.0002346261,0.00002585403,0.0001358555,0.0001700824,0.00004025349,0.003764236],"genre_scores_gemma":[0.9921455,0.00002483625,0.00736454,0.0000178644,0.00001440096,0.00004145316,0.0002918403,0.00001345296,0.00008611383],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008522114,"threshold_uncertainty_score":0.4504632,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06440927523988002,"score_gpt":0.3385601125192325,"score_spread":0.2741508372793524,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}