{"id":"W1863804530","doi":"10.1593/neo.13212","title":"IGFBP-4 Anti-Angiogenic and Anti-Tumorigenic Effects Are Associated with Anti-Cathepsin B Activity","year":2013,"lang":"en","type":"article","venue":"Neoplasia","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"","keywords":"Angiogenesis; Cancer research; Matrigel; Biology; Growth factor; Cathepsin; Chemistry; Biochemistry; Enzyme; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001245891,0.0004433847,0.0002315053,0.0003215917,0.0001349967,0.0002226678,0.0001506839,0.0001604982,0.002226998],"category_scores_gemma":[0.0001438755,0.0001357176,0.0003978934,0.000141078,0.0001847416,0.0001002489,0.0001279882,0.0005389076,0.0003435876],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003545918,"about_ca_system_score_gemma":0.0003036408,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001151633,"about_ca_topic_score_gemma":0.001346424,"domain_scores_codex":[0.9998945,0.00001942779,0.000006597848,0.00001315083,0.00003930113,0.00002698632],"domain_scores_gemma":[0.9999068,0.00001707131,0.00002694124,0.000009036001,0.00001976302,0.00002037689],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001235768,0.00002900291,0.0002808153,0.00006964395,0.00001200652,0.00006016993,0.000006209979,0.00003378841,0.9964532,0.00005575258,0.00004644108,0.002829546],"study_design_scores_gemma":[0.00002923523,0.0004810123,0.01248204,0.000004873128,0.0000391666,0.0009098148,0.00001281375,0.0003516218,0.9816481,0.00004123119,0.003995117,0.000004865062],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9793312,0.009950232,0.006114705,0.0002232769,0.00007046541,0.00005099104,0.0003762026,0.000154205,0.003728751],"genre_scores_gemma":[0.9892367,0.003186546,0.003826224,0.00006292138,0.00002431295,0.00003116662,0.0005317999,0.00001894762,0.003081388],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002226998,"threshold_uncertainty_score":0.007450104,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008530245128087111,"score_gpt":0.2129152872414216,"score_spread":0.2043850421133345,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}