{"id":"W1865947077","doi":"10.1111/j.1432-1033.2004.04280.x","title":"Analysis of the transcarbamoylation‐dehydration reaction catalyzed by the hydrogenase maturation proteins HypF and HypE","year":2004,"lang":"en","type":"article","venue":"European Journal of Biochemistry","topic":"Metalloenzymes and iron-sulfur proteins","field":"Energy","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Deutsche Forschungsgemeinschaft","keywords":"Chemistry; Active site; Hydrogenase; Biochemistry; Escherichia coli; Cysteine; Mutant; Cofactor; Catalysis; Enzyme; Stereochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001933048,0.0003910998,0.0003199443,0.0001658217,0.0001142571,0.0002693048,0.0002437706,0.0003534154,0.0004479407],"category_scores_gemma":[0.0004269366,0.0001735645,0.0003246494,0.0002160769,0.0001959168,0.0002637601,0.000225354,0.0006197559,0.0003202213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003065448,"about_ca_system_score_gemma":0.0001420235,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001241466,"about_ca_topic_score_gemma":0.0006153836,"domain_scores_codex":[0.9997922,0.00003588137,0.00001201616,0.00004257926,0.00007808064,0.00003931735],"domain_scores_gemma":[0.9996542,0.00008480103,0.00008996641,0.00003041454,0.00007954825,0.00006106881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009038061,0.0000151961,0.0003275928,0.00002722126,0.000009743499,0.00004311848,0.00001421849,0.00004023644,0.9987521,0.00005226859,0.00001603733,0.0006118193],"study_design_scores_gemma":[0.00001037755,0.0001563028,0.01140358,0.000003695819,0.00001370435,0.0005080464,0.00003511629,0.001580098,0.984985,0.00004256072,0.001251722,0.000009722563],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994835,0.0007308369,0.003496974,0.00005214588,0.000009419845,0.00001688988,0.0003993063,0.00003207251,0.0004274467],"genre_scores_gemma":[0.9917819,0.0004311091,0.004542585,0.00004229637,0.000008028595,0.0000229777,0.001628012,0.00004070143,0.001502243],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001241466,"threshold_uncertainty_score":0.002468467,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00673600252254726,"score_gpt":0.1902166735472674,"score_spread":0.1834806710247202,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}