{"id":"W1866311263","doi":"10.18433/j38s3h","title":"Subsequent Entry Biologics in Canada: Current State of the Science","year":2015,"lang":"en","type":"article","venue":"Journal of Pharmacy & Pharmaceutical Sciences","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University of Toronto","funders":"","keywords":"Interchangeability; Biosimilar; Reimbursement; Medicine; Quality (philosophy); Product (mathematics); Family medicine; Political science; Engineering; Health care; Law","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02367745,0.000806542,0.001569533,0.00524625,0.005417629,0.01495114,0.00389552,0.005926828,0.01325763],"category_scores_gemma":[0.02119439,0.0009182597,0.001160119,0.01022774,0.008439603,0.005805388,0.00298724,0.006725792,0.001481583],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.1067171,"about_ca_system_score_gemma":0.3763012,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.9521449,"about_ca_topic_score_gemma":0.9525625,"domain_scores_codex":[0.9829277,0.00119956,0.001226232,0.001310689,0.01046508,0.002870774],"domain_scores_gemma":[0.9202155,0.01096476,0.006774328,0.000729666,0.04925166,0.01206416],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007881484,0.0003864746,0.009779654,0.008733043,0.00009503136,0.0006242067,0.002523764,0.001183039,0.002124728,0.04347131,0.1944399,0.7358507],"study_design_scores_gemma":[0.00007654799,0.0003162905,0.01671466,0.00899651,0.00009887049,0.0004014085,0.004561273,0.0005592883,0.001525603,0.005131505,0.9614421,0.0001759792],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01019751,0.7389695,0.001312224,0.2081048,0.002720081,0.0001140597,0.00174733,0.0001892144,0.03664522],"genre_scores_gemma":[0.1105303,0.8242495,0.005591588,0.04395506,0.001244711,0.00007731542,0.002334796,0.0001096526,0.01190717],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.1067171,"threshold_uncertainty_score":0.77429,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.168999704754957,"score_gpt":0.4227012602694879,"score_spread":0.2537015555145309,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}