{"id":"W1866485899","doi":"10.1080/15384101.2015.1056948","title":"Role of stress-activated OCT4A in the cell fate decisions of embryonal carcinoma cells treated with etoposide","year":2015,"lang":"en","type":"article","venue":"Cell Cycle","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Biology; Etoposide; Embryonal carcinoma; Cell biology; Cell fate determination; Cancer research; Cellular differentiation; Transcription factor; Genetics; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007623271,0.0001658274,0.0002005751,0.0002193573,0.0001585461,0.000331087,0.00007838801,0.0001724428,0.0008180202],"category_scores_gemma":[0.00009981032,0.0001081138,0.0001657122,0.0001258856,0.0001346847,0.0001881659,0.0001280404,0.0002832494,0.0002041817],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002728223,"about_ca_system_score_gemma":0.0001711714,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008540286,"about_ca_topic_score_gemma":0.0008003669,"domain_scores_codex":[0.9999255,0.00001586439,0.000009545644,0.00001370197,0.00001756359,0.0000178609],"domain_scores_gemma":[0.9999391,0.00001116133,0.00001442149,0.000007227566,0.00001139791,0.00001664654],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001750157,0.00001217351,0.0005318001,0.00001608796,0.000003158236,0.00005657079,0.00002071393,0.00004714358,0.9984144,0.00004478238,0.0000139817,0.0006641441],"study_design_scores_gemma":[0.000009549502,0.000136815,0.02113283,0.000005838556,0.000009850352,0.000165698,0.00007917565,0.00100535,0.9759899,0.00005573329,0.001403786,0.000005458787],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967852,0.001117086,0.0006400298,0.00004868052,0.00001450841,0.00001211158,0.0003200611,0.00002210213,0.001040192],"genre_scores_gemma":[0.9973858,0.0004709472,0.0004012447,0.00002806005,0.000003766693,0.00001534566,0.0003281774,0.000006464843,0.001360219],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008540286,"threshold_uncertainty_score":0.002736509,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0122695319888099,"score_gpt":0.222601336549868,"score_spread":0.2103318045610581,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}