{"id":"W1867840951","doi":"10.1161/circresaha.115.307023","title":"Disruption of RIP1-FADD Complexes by MicroRNA-103/107 Provokes Necrotic Cardiac Cell Death","year":2015,"lang":"en","type":"letter","venue":"Circulation Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Boniface Hospital","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Heart and Stroke Foundation of Canada","keywords":"FADD; Medicine; Biomedical sciences; Programmed cell death; Pathophysiology; Apoptosis; Heart failure; Gerontology; Internal medicine; Pathology; Biology; Caspase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009838647,0.0003113608,0.0007400115,0.0005150798,0.000160655,0.00006832551,0.0002860712,0.0007175161,0.0003417928],"category_scores_gemma":[0.0001337225,0.0002878669,0.0002959225,0.0004537279,0.0003105168,0.0001179398,0.00008118863,0.001669468,0.0002334596],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003665231,"about_ca_system_score_gemma":0.0006658767,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003982055,"about_ca_topic_score_gemma":0.000001485349,"domain_scores_codex":[0.9957925,0.0006049474,0.0005259766,0.0005807227,0.001864346,0.0006314775],"domain_scores_gemma":[0.9972039,0.0002614596,0.0002216336,0.0008836494,0.00121044,0.0002189127],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001081446,0.0001938364,0.01167739,0.001240272,0.0002108605,0.00006680519,0.0002867351,0.00001634474,0.04625902,0.00002935269,0.9391804,0.0007308553],"study_design_scores_gemma":[0.00316464,0.0005940641,0.06453041,0.0007364728,0.0004372694,0.00002356897,0.0002316642,0.0007683052,0.01754444,0.002114602,0.90911,0.0007446174],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8764482,0.01408518,0.0003080663,0.08451798,0.0006645026,0.005634322,0.0008530545,0.0002072309,0.01728147],"genre_scores_gemma":[0.9597624,0.0003723895,0.0001259719,0.01799215,0.00271276,0.0002244398,0.008021836,0.0001797812,0.01060829],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08331418,"threshold_uncertainty_score":0.9999573,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1030611027462461,"score_gpt":0.3852731842913473,"score_spread":0.2822120815451012,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}