{"id":"W1867840951","doi":"10.1161/circresaha.115.307023","title":"Disruption of RIP1-FADD Complexes by MicroRNA-103/107 Provokes Necrotic Cardiac Cell Death","year":2015,"lang":"en","type":"letter","venue":"Circulation Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Boniface Hospital","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Heart and Stroke Foundation of Canada","keywords":"FADD; Medicine; Biomedical sciences; Programmed cell death; Pathophysiology; Apoptosis; Heart failure; Gerontology; Internal medicine; Pathology; Biology; Caspase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001039924,0.0005980206,0.0009358815,0.0002282395,0.0008766421,0.001488801,0.0003714077,0.007670647,0.002583707],"category_scores_gemma":[0.003417573,0.0002862154,0.0006869039,0.0001399579,0.0009679132,0.000562874,0.0004168456,0.006444679,0.001513902],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001395888,"about_ca_system_score_gemma":0.0004571399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002913534,"about_ca_topic_score_gemma":0.0005117949,"domain_scores_codex":[0.9994037,0.0001924478,0.00005485301,0.00006177626,0.0001868895,0.0001002951],"domain_scores_gemma":[0.9991186,0.0005299602,0.00009711376,0.00006878002,0.00007017003,0.0001153499],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005472531,0.001063786,0.00625277,0.000585877,0.0002822056,0.09987276,0.0004487083,0.001198027,0.1045247,0.02161564,0.5999461,0.158737],"study_design_scores_gemma":[0.005830519,0.006121107,0.0173412,0.0004510973,0.0004099443,0.09231851,0.0007636276,0.01030716,0.1084907,0.03459754,0.7230978,0.0002707564],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.1300564,0.02067667,0.007031644,0.7178406,0.061901,0.0003412507,0.000450248,0.001229462,0.06047281],"genre_scores_gemma":[0.5987865,0.007226708,0.003788287,0.3359967,0.03221591,0.00033676,0.0002200642,0.0001017288,0.02132721],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.007670647,"threshold_uncertainty_score":0.0101279,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1030611027462461,"score_gpt":0.3852731842913473,"score_spread":0.2822120815451012,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}