{"id":"W1868560008","doi":"10.1091/mbc.e02-03-0122","title":"Clastosome: A Subtype of Nuclear Body Enriched in 19S and 20S Proteasomes, Ubiquitin, and Protein Substrates of Proteasome","year":2002,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":134,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Uppsala Universitet; University of Dundee; McGill University; University of Pennsylvania","keywords":"Proteasome; Proteolysis; Biology; Ubiquitin; Cell biology; Nuclear protein; Transcription factor; Cell nucleus; Protein degradation; Nuclear transport; Biochemistry; Nucleus; Enzyme; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001182479,0.0003321423,0.0005102978,0.001112219,0.0008007811,0.0009791818,0.0004616431,0.0005180716,0.002135647],"category_scores_gemma":[0.0001404794,0.0001816163,0.0003219039,0.0007589922,0.0004414515,0.0008263844,0.0005625107,0.000324902,0.001404771],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003844509,"about_ca_system_score_gemma":0.0002797892,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001007619,"about_ca_topic_score_gemma":0.001487857,"domain_scores_codex":[0.9998536,0.000008039555,0.00001160692,0.00005318726,0.00003623675,0.00003735],"domain_scores_gemma":[0.9998388,0.000009091154,0.00004129486,0.00002680318,0.00003352015,0.0000504772],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005038585,0.00004566394,0.007332535,0.0002433561,0.00002991078,0.002000219,0.0001469774,0.0001116166,0.9547802,0.002479346,0.00163531,0.03069094],"study_design_scores_gemma":[0.00005538929,0.0004806469,0.1194992,0.000119769,0.00009877666,0.04759032,0.0004000817,0.001074357,0.6222476,0.003281939,0.2050672,0.00008467804],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8809766,0.05516039,0.0381365,0.0004212645,0.0004062529,0.0002634166,0.004360843,0.001389029,0.01888575],"genre_scores_gemma":[0.9260122,0.01446691,0.02428514,0.0003594074,0.0001789448,0.0001216017,0.007223873,0.0001157087,0.0272363],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002135647,"threshold_uncertainty_score":0.007144392,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007497027327093898,"score_gpt":0.2081797027160428,"score_spread":0.2006826753889489,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}