{"id":"W1869019363","doi":"10.1038/npp.2015.292","title":"Reductions in Cortico-Striatal Hyperconnectivity Accompany Successful Treatment of Obsessive-Compulsive Disorder with Dorsomedial Prefrontal rTMS","year":2015,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Obsessive-Compulsive Spectrum Disorders","field":"Psychology","cited_by":152,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research; National Institutes of Health; H. Lundbeck A/S; Eli Lilly Canada; Bristol-Myers Squibb; Eli Lilly and Company; AstraZeneca; National Alliance for Research on Schizophrenia and Depression; Louis and Harold Price Foundation; Klarman Family Foundation; Pfizer; Brain and Behavior Research Foundation","keywords":"Transcranial magnetic stimulation; Psychology; Ventral striatum; Functional magnetic resonance imaging; Neuroscience; Obsessive compulsive; Deep brain stimulation; Prefrontal cortex; Treatment-resistant depression; Temporal lobe; Major depressive disorder; Stimulation; Psychiatry; Striatum; Amygdala; Medicine; Dopamine; Cognition; Internal medicine; Disease; Epilepsy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001125475,0.0002100148,0.0003058279,0.0002167612,0.0000981023,0.0001165203,0.00009251998,0.0001462648,0.0006126425],"category_scores_gemma":[0.000446754,0.00009248118,0.0001068231,0.00008876227,0.0001511419,0.00006340599,0.00006996778,0.0001599494,0.00006340678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001383151,"about_ca_system_score_gemma":0.00008775737,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001397513,"about_ca_topic_score_gemma":0.004157841,"domain_scores_codex":[0.9999406,0.00001808912,0.00000592638,0.00001137554,0.00001437422,0.00000948832],"domain_scores_gemma":[0.9998995,0.0000282091,0.00003869622,0.000006307148,0.000009293969,0.00001793962],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.006220551,0.001339536,0.1466389,0.0002758976,0.0004615321,0.00207691,0.0007670181,0.001238573,0.7205387,0.00006805833,0.0004221795,0.1199522],"study_design_scores_gemma":[0.000178018,0.003714044,0.9852807,0.000009305927,0.00008396096,0.001758234,0.0001269806,0.001112076,0.007361181,0.00004301019,0.0003235229,0.000009015951],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994106,0.000143674,0.0001510713,0.0000156721,0.000001332611,0.00001265135,0.0000187556,0.00001332154,0.0002329808],"genre_scores_gemma":[0.9995655,0.00007682513,0.0001808576,0.00001888559,0.000002347074,0.000008312486,0.00004477104,0.000002486349,0.00009979727],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001397513,"threshold_uncertainty_score":0.002778709,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02505763785550993,"score_gpt":0.323931664025156,"score_spread":0.2988740261696461,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}