{"id":"W1869019363","doi":"10.1038/npp.2015.292","title":"Reductions in Cortico-Striatal Hyperconnectivity Accompany Successful Treatment of Obsessive-Compulsive Disorder with Dorsomedial Prefrontal rTMS","year":2015,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Obsessive-Compulsive Spectrum Disorders","field":"Psychology","cited_by":152,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research; National Institutes of Health; H. Lundbeck A/S; Eli Lilly Canada; Bristol-Myers Squibb; Eli Lilly and Company; AstraZeneca; National Alliance for Research on Schizophrenia and Depression; Louis and Harold Price Foundation; Klarman Family Foundation; Pfizer; Brain and Behavior Research Foundation","keywords":"Transcranial magnetic stimulation; Psychology; Ventral striatum; Functional magnetic resonance imaging; Neuroscience; Obsessive compulsive; Deep brain stimulation; Prefrontal cortex; Treatment-resistant depression; Temporal lobe; Major depressive disorder; Stimulation; Psychiatry; Striatum; Amygdala; Medicine; Dopamine; Cognition; Internal medicine; Disease; Epilepsy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001261401,0.0006145368,0.001033452,0.0005747189,0.000109834,0.00002650941,0.0005173552,0.0002391472,0.001105558],"category_scores_gemma":[0.00007281303,0.0005419272,0.0001926908,0.001035013,0.0007751341,0.0003290464,0.00008748064,0.0004962906,0.0001963951],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003486814,"about_ca_system_score_gemma":0.0003160508,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00166536,"about_ca_topic_score_gemma":0.001216629,"domain_scores_codex":[0.9957854,0.000896873,0.0007935784,0.001193982,0.0003864612,0.0009437361],"domain_scores_gemma":[0.9977643,0.0004190049,0.0005392871,0.0006569551,0.0002180882,0.0004023875],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02576203,0.0252881,0.8278135,0.00006032431,0.001606155,0.001842374,0.02184886,0.003866908,0.04012668,0.002147697,0.003763956,0.04587337],"study_design_scores_gemma":[0.04482141,0.007488613,0.9320788,0.00002461883,0.000360153,0.0003931873,0.006365449,0.0001881741,0.0012988,0.0004174068,0.005676877,0.0008865223],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9843463,0.0005661178,0.0001045872,0.0009161097,0.006375414,0.001533237,0.0001263167,0.0001438987,0.005887978],"genre_scores_gemma":[0.9981828,0.00007675804,0.0001996331,0.000159817,0.0005028531,0.0004313825,0.00006192602,0.0001038543,0.0002809324],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1042653,"threshold_uncertainty_score":0.9998076,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02505763785550993,"score_gpt":0.323931664025156,"score_spread":0.2988740261696461,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}